SCHEMBL16007758

SCHEMBL16007758

CO[Si](C)(CCCC1CC2CCC1C2)OC

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.34
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33
OPRK1 P41145 8/20 0.32
HPGD P15428 1/20 0.32
OPRM1 P35372 1/20 0.31
OPRD1 P41143 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16007797 0.94 LMNA (0.33) LMNAMEN1NPC1RAB9AKMT2A
SCHEMBL16007717 0.90 LMNA (0.36) LMNAMEN1NPC1RAB9AKMT2A
SCHEMBL16007865 0.85 LMNA (0.35) LMNAMEN1NPC1RAB9AKMT2A
SCHEMBL8611993 0.80 LMNA (0.36) LMNAMEN1NPC1RAB9AKMT2A
SCHEMBL16007750 0.80 LMNA (0.34) LMNAOPRK1OPRM1OPRD1
SCHEMBL16007804 0.79 LMNA (0.34) LMNAOPRK1OPRM1OPRD1
SCHEMBL16007813 0.78 EPHX2 (0.30) OPRK1
SCHEMBL14770739 0.77 LMNA (0.36) LMNAMEN1NPC1RAB9AKMT2A
SCHEMBL16007781 0.75 EPHX2 (0.32) OPRK1
SCHEMBL3447574 0.75 MEN1 (0.39) MEN1NPC1RAB9AKMT2AOPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8975350-B2 Polymerizable composition, resin moldings and manufacturing process therefor, and laminates ZEON CORPORATION (JP) 2015-03-10 US disclosed
US-20140256878-A1 POLYMERIZABLE COMPOSITION, RESIN MOLDINGS AND MANUFACTURING PROCESS THEREFOR, AND LAMINATES ZEON CORPORATION (JP) 2014-09-11 US disclosed