Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16007758 | 0.80 | LMNA (0.34) | LMNAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL16007797 | 0.78 | LMNA (0.33) | LMNAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL16007717 | 0.77 | LMNA (0.36) | LMNAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL24238285 | 0.73 | MEN1 (0.39) | LMNAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL537901 | 0.70 | CYP2C19 (0.33) | MEN1KMT2A | |
| SCHEMBL25475058 | 0.70 | MEN1 (0.39) | MEN1KMT2ANPC1RAB9AHPGD | |
| SCHEMBL25476731 | 0.69 | MEN1 (0.36) | LMNAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL13390677 | 0.69 | MEN1 (0.41) | LMNAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL26031878 | 0.69 | MAOA (0.50) | LMNAMEN1KMT2ACHRNB2CHRNB4 | |
| SCHEMBL1638782 | 0.68 | CYP2C19 (0.32) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9194596-A | — | — | None | — | — | JP | disclosed |
| US-5725790-A | AMINOALKYLNORBORNANE DERIVATIVE MONOMERS; DISCOLORATION INHIBITION, FLEXIBILITY, WATER ABSORBENT | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1998-03-10 | — | — | US | disclosed |
| JP-H09194596-A | NEW ORGANOPOLYSILOXANE AND FIBER TREATING AGENT COMPOSITION COMPRISING THE SAME AS MAIN COMPONENT | SHIN ETSU CHEM CO LTD | 1997-07-29 | — | — | JP | disclosed |