SCHEMBL16007804

SCHEMBL16007804

CO[Si](CCCCCCC1CC2CCC1C2)(OC)OC

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.34
OPRK1 P41145 9/20 0.33
OPRM1 P35372 1/20 0.33
OPRD1 P41143 1/20 0.33
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TP53 P04637 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
HSD17B10 Q99714 1/20 0.31
EPHX2 P34913 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16007750 0.98 LMNA (0.34) LMNAOPRK1OPRM1OPRD1KDM4E
SCHEMBL16007865 0.93 LMNA (0.35) LMNAOPRK1OPRM1OPRD1KDM4E
SCHEMBL14770739 0.86 LMNA (0.36) LMNAOPRK1OPRM1OPRD1KDM4E
SCHEMBL16007797 0.86 LMNA (0.33) LMNAOPRK1OPRM1OPRD1
SCHEMBL16007365 0.84 EPHX2 (0.31) OPRK1EPHX2
SCHEMBL16007690 0.83 EPHX2 (0.31) OPRK1EPHX2
SCHEMBL16007758 0.79 LMNA (0.34) LMNAOPRK1OPRM1OPRD1
SCHEMBL3447574 0.78 MEN1 (0.39) OPRK1EPHX2
SCHEMBL16007781 0.77 EPHX2 (0.32) OPRK1EPHX2
SCHEMBL16007799 0.77 EPHX2 (0.30) EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8975350-B2 Polymerizable composition, resin moldings and manufacturing process therefor, and laminates ZEON CORPORATION (JP) 2015-03-10 US disclosed
US-20140256878-A1 POLYMERIZABLE COMPOSITION, RESIN MOLDINGS AND MANUFACTURING PROCESS THEREFOR, AND LAMINATES ZEON CORPORATION (JP) 2014-09-11 US disclosed
CN-103717671-A Polymerizable composition, resin moldings and manufacturing process therefor, and laminates ZEON CORP 2014-04-09 CN disclosed