⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9219179 | 0.79 | CA2 (0.39) | — | |
| SCHEMBL5208766 | 0.77 | — | — | |
| SCHEMBL5403877 | 0.76 | ZDHHC7 (0.37) | — | |
| SCHEMBL6859111 | 0.76 | ZDHHC7 (0.41) | — | |
| SCHEMBL11027982 | 0.76 | ZDHHC7 (0.41) | — | |
| SCHEMBL26947095 | 0.75 | — | — | |
| SCHEMBL17354689 | 0.73 | — | — | |
| SCHEMBL28530995 | 0.73 | — | — | |
| SCHEMBL6309278 | 0.73 | — | — | |
| SCHEMBL17375326 | 0.73 | CA2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102627527-B | Preparation method of unsaturated fatty chain alcohol and intermediate thereof | SHANGHAI CAIERWEN BIOCHEMICAL TECHNOLOGY CO LTD | 2014-08-06 | — | — | CN | disclosed |
| US-7919523-B2 | Inhibitors of aspartyl protease | VERTEX PHARMACEUTICALS, INC. (US) | 2011-04-05 | — | — | US | disclosed |
| US-20090042973-A1 | Inhibitors of aspartyl protease | VERTEX PHARMACEUTICALS INCORPORATED | 2009-02-12 | — | — | US | disclosed |
| US-7442718-B2 | Inhibitors of aspartyl protease | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2008-10-28 | — | — | US | disclosed |
| EP-1727785-A1 | PHENYL INDAN DERIVATIVES | H.Lundbeck A/S (DK) | 2006-12-06 | — | — | EP | disclosed |
| EP-1637518-A2 | Inhibitors of aspartyl protease | Vertex Pharmaceuticals Incorporated (US) | 2006-03-22 | — | — | EP | disclosed |
| EP-1159278-B1 | INHIBITORS OF ASPARTYL PROTEASE | VERTEX PHARMA (US) | 2005-11-30 | — | — | EP | disclosed |
| WO-2005087708-A1 | PHENYL INDAN DERIVATIVES | H. LUNDBECK A/S (DK) | 2005-09-22 | — | — | WO | disclosed |
| EP-0990653-B1 | 2-OXOIMIDAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-09-15 | — | — | EP | disclosed |
| WO-2004063292-A2 | ANTI-FOULING SOL-GEL COATINGS CONTAINING DENDRIMERS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEWYORK (US) | 2004-07-29 | — | — | WO | disclosed |
| WO-1996039407-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-12-12 | — | — | WO | disclosed |
| WO-1996037492-A1 | ISOXAZOLINE AND ISOXAZOLE DERIVATIVES AS INTEGRIN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-11-28 | — | — | WO | disclosed |
| EP-0723545-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-07-31 | — | — | EP | disclosed |
| WO-1995010519-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1995-04-20 | — | — | WO | disclosed |
| US-5405864-A | Chemotherapeutic maleimides | SYNTEX (U.S.A.) INC. (US) | 1995-04-11 | — | — | US | disclosed |
| EP-0136010-A2 | Photographic element containing a 4-hydroxyalkyl-substituted 1-phenyl-3-pyrazolidinone electron transfer agent | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1985-04-03 | — | — | EP | disclosed |
| EP-0134696-A1 | Preparation of 4-substituted-3-pyrazolidinones | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1985-03-20 | — | — | EP | disclosed |
| EP-0134695-A1 | Photographic element containing a 4-hydroxyalkyl-substituted 1-phenyl-3-pyrazolidinone electron transfer agent | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1985-03-20 | — | — | EP | disclosed |
| US-4481287-A | COLOR DIFFUSION TRANSFER OR BLACK AND WHITE PHOTOGRAPHY | EASTMAN KODAK COMPANY (US) | 1984-11-06 | — | — | US | disclosed |
| US-4471045-A | 4-Hydroxyalkyl-substituted 3-pyrazolidinone electron transfer agents | EASTMAN KODAK COMPANY (US) | 1984-09-11 | — | — | US | disclosed |