Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.40 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 4/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11027982 | 1.00 | ZDHHC7 (0.41) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL5403877 | 0.96 | ZDHHC7 (0.37) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL9219179 | 0.92 | CA2 (0.39) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL14834118 | 0.81 | CA2 (0.36) | ZDHHC7CA2GPR84LMNA | |
| SCHEMBL8063012 | 0.79 | FAAH (0.37) | FAAHCA2LMNACNR1CNR2 | |
| SCHEMBL9055975 | 0.79 | SMPD1 (0.37) | CA2LMNA | |
| SCHEMBL29910754 | 0.78 | GPR84 (0.37) | CA2GPR84FFAR1LMNAMAPT | |
| SCHEMBL9117823 | 0.78 | GPR84 (0.37) | CA2GPR84FFAR1LMNAMAPT | |
| SCHEMBL30116202 | 0.77 | OPRM1 (0.37) | FAAHCA2LMNACNR1CNR2 | |
| SCHEMBL5208766 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6790971-B1 | AMIDE OR CARBAMATE FUNCTION AT 11 BETA-POSITION; CLAIMED 3-ONE-DIENE INTERMEDIATE HAS HYDROXYMETHYLALKYL GROUP ON 11 POSITION; ANTIPROGESTOMIMETIC; HORMONE-DEPENDENT TUMORS; ANIMAL HUSBANDRY | AVENTIS PHARMA S.A. (FR) | 2004-09-14 | — | — | US | disclosed |
| US-5707982-A | ANTITUMOR | ROUSSEL UCLAF (FR) | 1998-01-13 | — | — | US | disclosed |
| US-5290771-A | 19-nor-steroids | ROUSSEL UCLAF (FR) | 1994-03-01 | — | — | US | disclosed |
| EP-0384842-B1 | 19-Nor steroids substituted at position 11-beta by a hydrocarbon chain containing an amide or carbamate group, their preparation, intermediates, their use as medicaments and pharmaceutical compositions containing them | ROUSSEL UCLAF (FR) | 1993-12-29 | — | — | EP | disclosed |
| US-5149696-A | Antiestrogens | ROUSSEL UCLAF (FR) | 1992-09-22 | — | — | US | disclosed |
| EP-0384842-A1 | 19-Nor steroids substituted at position 11-beta by a hydrocarbon chain containing an amide or carbamate group, their preparation, intermediates, their use as medicaments and pharmaceutical compositions containing them | ROUSSEL-UCLAF (FR) | 1990-08-29 | — | — | EP | disclosed |