Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | CTSG | P08311 | 1/20 | 0.30 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.30 |
| ▸ | CMA1 | P23946 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6859111 | 0.96 | ZDHHC7 (0.41) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL11027982 | 0.96 | ZDHHC7 (0.41) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL9219179 | 0.92 | CA2 (0.39) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL9055975 | 0.79 | SMPD1 (0.37) | CA2OPRM1 | |
| SCHEMBL30116202 | 0.77 | OPRM1 (0.37) | FAAHCA2OPRM1 | |
| SCHEMBL14834118 | 0.77 | CA2 (0.36) | ZDHHC7CA2OPRM1 | |
| SCHEMBL5208766 | 0.76 | — | — | |
| SCHEMBL1600875 | 0.76 | — | — | |
| SCHEMBL8063012 | 0.76 | FAAH (0.37) | FAAHCA2OPRM1 | |
| SCHEMBL7491712 | 0.76 | CA2 (0.35) | CA2PRSS1CTSGCTRB1CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169611-B2 | Programmable genotoxic agents and uses therefor | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-01-30 | — | — | US | disclosed |
| US-20030220311-A1 | Programmable genotoxic agents and uses therefor | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2003-11-27 | — | — | US | disclosed |
| US-6500669-B1 | FOR SELECTIVELY KILLING A SUBPOPULATION OF CELLS IN A HETEROGENOUS CELL POPULATION; ALKYLATING AGENTS OR HEAVY METAL COORDINATION COMPOUNDS LINKED TO A COMPOUND THAT BINDS TO STEROID RECEPTOR | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2002-12-31 | — | — | US | disclosed |