SCHEMBL16010033

SCHEMBL16010033

COCOc1cc(C)c(Br)c(OCOC)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
LMNA P02545 2/20 0.37
ROR1 Q01973 1/20 0.36
HPGD P15428 1/20 0.36
MAPT P10636 4/20 0.35
HDAC3 O15379 1/20 0.34
HDAC4 P56524 1/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC7 Q8WUI4 1/20 0.34
HDAC2 Q92769 1/20 0.34
HDAC10 Q969S8 1/20 0.34
HDAC11 Q96DB2 1/20 0.34
HDAC8 Q9BY41 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
HDAC9 Q9UKV0 1/20 0.34
HDAC5 Q9UQL6 1/20 0.34
STAT3 P40763 1/20 0.33
NOD2 Q9HC29 1/20 0.33
TSHR P16473 2/20 0.33
TNFRSF1A P19438 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL206233 0.88 ALDH1A1 (0.46) ALDH1A1LMNAROR1HPGDMAPT
SCHEMBL27755373 0.80 ALDH1A1 (0.41) ALDH1A1LMNAHPGDMAPTSTAT3
SCHEMBL17385939 0.79 ALDH1A1 (0.40) ALDH1A1LMNAHPGDMAPTSTAT3
SCHEMBL2025203 0.79 HDAC3 (0.33) ALDH1A1ROR1MAPTHDAC3HDAC4
SCHEMBL2024930 0.77 PDE4A (0.34) ALDH1A1ROR1MAPTHDAC3HDAC4
SCHEMBL2866529 0.77 HDAC3 (0.32) ALDH1A1ROR1HDAC3HDAC4HDAC1
SCHEMBL17385919 0.77 ALDH1A1 (0.39) ALDH1A1LMNAHPGDMAPTSTAT3
SCHEMBL4378990 0.76 HDAC3 (0.32) ROR1HDAC3HDAC4HDAC1HDAC7
SCHEMBL19616974 0.76 GRM5 (0.33) ALDH1A1LMNAROR1HPGDMAPT
SCHEMBL12563254 0.75 EGFR (0.44) TSHRPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10470986-B2 Resorcinol compounds for dermatological use CONOPCO, INC. (US) 2019-11-12 US disclosed
EP-2964182-B1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE UNILEVER PLC A COMPANY REGISTERED IN ENGLAND AND WALES UNDER COMPANY NO 41424 OF (GB) 2018-02-14 EP disclosed
EP-2964182-B1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE UNILEVER PLC A COMPANY REGISTERED IN ENGLAND AND WALES UNDER COMPANY NO 41424 OF (GB) 2018-02-14 EP disclosed
EP-2964182-A2 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE Unilever PLC, a company registered in England and Wales under company no. 41424 of (GB) 2016-01-13 EP disclosed
US-20160000669-A1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE CONOPCO, INC., D/B/A UNILEVER (US) 2016-01-07 US disclosed
US-20160000669-A1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE CONOPCO, INC., D/B/A UNILEVER (US) 2016-01-07 US disclosed
US-20160000669-A1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE CONOPCO, INC., D/B/A UNILEVER (US) 2016-01-07 US disclosed
WO-2014138471-A2 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE AMPERE LIFE SCIENCES, INC. (US) 2014-09-12 WO disclosed
WO-2014138471-A2 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE AMPERE LIFE SCIENCES, INC. (US) 2014-09-12 WO disclosed
US-20140256830-A1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE UNILEVER N.V. (NL) 2014-09-11 US disclosed
US-20140256830-A1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE UNILEVER N.V. (NL) 2014-09-11 US disclosed
US-20140256830-A1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE UNILEVER N.V. (NL) 2014-09-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160000669-A1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE NQO1, RBP4, KEAP1 ALDH1A1 415/4885LMNA 338/4885ROR1 725/4885
US-20140256830-A1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE NQO1, RBP4, KEAP1 ALDH1A1 415/4885LMNA 338/4885ROR1 725/4885
US-10470986-B2 Resorcinol compounds for dermatological use NQO1, RBP4, KEAP1 ALDH1A1 415/4885LMNA 338/4885ROR1 725/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.