Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.46 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.46 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.46 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.46 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.46 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | CTSV | O60911 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | CTSC | P53634 | 1/20 | 0.41 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21697602 | 1.00 | LMNA (0.51) | LMNAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL21218201 | 0.87 | LMNA (0.51) | LMNAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL16018599 | 0.85 | PSEN1 (0.47) | LMNAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL16018622 | 0.85 | PSEN1 (0.47) | LMNAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL16018601 | 0.85 | PSEN1 (0.47) | LMNAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL524084 | 0.82 | LMNA (0.58) | LMNABCHEACHECTSVCTSL | |
| SCHEMBL28102964 | 0.82 | LMNA (0.58) | LMNABCHEACHECTSVCTSL | |
| SCHEMBL20107268 | 0.80 | PSEN1 (0.49) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL20056422 | 0.79 | PDE4D (0.42) | LMNAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL20056463 | 0.78 | LMNA (0.40) | LMNAPSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020129900-A1 | METHOD FOR PRODUCING C-ARYLHYDROXY GLYCOXIDE DERIVATIVE | 株式会社トクヤマ | 2020-06-25 | — | — | WO | disclosed |
| EP-2968258-B1 | DUAL SGLT1/SGLT2 INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-02-12 | — | — | EP | disclosed |
| EP-2968258-B1 | DUAL SGLT1/SGLT2 INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-02-12 | — | — | EP | disclosed |
| EP-2968258-A1 | DUAL SGLT1/SGLT2 INHIBITORS | Janssen Pharmaceutica, N.V. (BE) | 2016-01-20 | — | — | EP | disclosed |
| US-9012412-B2 | Dual SGLT1/SGLT2 inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2015-04-21 | — | — | US | disclosed |
| WO-2014164286-A1 | DUAL SGLT1/SGLT2 INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2014-10-09 | — | — | WO | disclosed |
| US-20140256657-A1 | DUAL SGLT1/SGLT2 INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2014-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256657-A1 | DUAL SGLT1/SGLT2 INHIBITORS | SLC5A1, SLC5A2, GLP1R | LMNA 4631/4885PSEN1 3587/4885PSEN2 3514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.