Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | CTSV | O60911 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20056311 | 0.84 | ALDH1A1 (0.39) | PDE4DLMNABCHEACHEELANE | |
| SCHEMBL20056463 | 0.82 | LMNA (0.40) | PDE4DLMNABCHEACHEPSEN1 | |
| SCHEMBL16010060 | 0.79 | LMNA (0.51) | PDE4DLMNABCHEACHEPSEN1 | |
| SCHEMBL21697602 | 0.79 | LMNA (0.51) | PDE4DLMNABCHEACHEPSEN1 | |
| SCHEMBL16027479 | 0.76 | BCHE (0.45) | PDE4DBCHEACHEELANEPTPN1 | |
| SCHEMBL16027476 | 0.76 | BCHE (0.45) | PDE4DBCHEACHEELANEPTPN1 | |
| SCHEMBL5838951 | 0.76 | BCHE (0.45) | PDE4DBCHEACHEELANEPTPN1 | |
| SCHEMBL5838955 | 0.76 | BCHE (0.45) | PDE4DBCHEACHEELANEPTPN1 | |
| SCHEMBL16027482 | 0.76 | BCHE (0.45) | PDE4DBCHEACHEELANEPTPN1 | |
| SCHEMBL23047646 | 0.72 | PDE4D (0.52) | PDE4DLMNABCHEACHESLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970353-B1 | MANNOSE DERIVATIVES FOR TREATING BACTERIAL INFECTIONS | VERTEX PHARMA (US) | 2018-04-18 | — | — | EP | disclosed |