SCHEMBL16010402

SCHEMBL16010402

CCC(C)c1c(C)cc(O)cc1O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.42
CYP3A4 P08684 5/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
TSHR P16473 1/20 0.41
ACHE P22303 2/20 0.39
ALOX15 P16050 2/20 0.39
USP2 O75604 1/20 0.39
ALDH1A1 P00352 1/20 0.39
GAA P10253 1/20 0.39
PKM P14618 1/20 0.39
HPGD P15428 1/20 0.39
HSD17B10 Q99714 1/20 0.39
CHRM1 P11229 1/20 0.38
MAOA P21397 1/20 0.38
TBXA2R P21731 1/20 0.38
ADRA1A P35348 1/20 0.38
HTR2B P41595 1/20 0.38
RORC P51449 1/20 0.38
NR1H2 P55055 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16018022 0.89 CYP3A4 (0.42) RXRACYP3A4SMN1; SMN2TDP1TSHR
SCHEMBL20621450 0.89 RXRA (0.46) RXRACYP3A4SMN1; SMN2TDP1TSHR
SCHEMBL31545466 0.83 CYP3A4 (0.42) RXRACYP3A4SMN1; SMN2TDP1ACHE
SCHEMBL24785027 0.82 CYP3A4 (0.46) RXRACYP3A4SMN1; SMN2TDP1TSHR
SCHEMBL29427938 0.80 CYP3A4 (0.43) CYP3A4SMN1; SMN2TDP1ACHEALOX15
SCHEMBL16010550 0.80 CYP3A4 (0.43) CYP3A4SMN1; SMN2TDP1ACHEALOX15
SCHEMBL10048630 0.78 EGFR (0.45) CYP3A4SMN1; SMN2TDP1ACHEALOX15
SCHEMBL4912196 0.78 TSHR (0.39) RXRACYP3A4TSHRACHEALOX15
SCHEMBL39051 0.76 CYP3A4 (0.42) RXRACYP3A4SMN1; SMN2TDP1TSHR
SCHEMBL5175941 0.76 CYP3A4 (0.42) CYP3A4SMN1; SMN2TDP1TSHRACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10470986-B2 Resorcinol compounds for dermatological use CONOPCO, INC. (US) 2019-11-12 US disclosed
US-10470986-B2 Resorcinol compounds for dermatological use CONOPCO, INC. (US) 2019-11-12 US disclosed
EP-2964182-B1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE UNILEVER PLC A COMPANY REGISTERED IN ENGLAND AND WALES UNDER COMPANY NO 41424 OF (GB) 2018-02-14 EP disclosed
EP-2964182-B1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE UNILEVER PLC A COMPANY REGISTERED IN ENGLAND AND WALES UNDER COMPANY NO 41424 OF (GB) 2018-02-14 EP disclosed
US-20160000669-A1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE CONOPCO, INC., D/B/A UNILEVER (US) 2016-01-07 US disclosed
US-20160000669-A1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE CONOPCO, INC., D/B/A UNILEVER (US) 2016-01-07 US disclosed
US-20160000669-A1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE CONOPCO, INC., D/B/A UNILEVER (US) 2016-01-07 US disclosed
WO-2014138471-A2 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE AMPERE LIFE SCIENCES, INC. (US) 2014-09-12 WO disclosed
US-20140256830-A1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE UNILEVER N.V. (NL) 2014-09-11 US disclosed
US-20140256830-A1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE UNILEVER N.V. (NL) 2014-09-11 US disclosed
US-20140256830-A1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE UNILEVER N.V. (NL) 2014-09-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160000669-A1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE NQO1, RBP4, KEAP1 RXRA 30/4885CYP3A4 1742/4885SMN1; SMN2 4162/4885
US-20140256830-A1 RESORCINOL COMPOUNDS FOR DERMATOLOGICAL USE NQO1, RBP4, KEAP1 RXRA 30/4885CYP3A4 1742/4885SMN1; SMN2 4162/4885
US-10470986-B2 Resorcinol compounds for dermatological use NQO1, RBP4, KEAP1 RXRA 30/4885CYP3A4 1742/4885SMN1; SMN2 4162/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.