Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 11/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 10/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 8/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 8/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 8/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 8/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 8/20 | 0.57 |
| ▸ | NCOR2 | Q9Y618 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15480414 | 0.89 | HDAC1 (0.69) | LMNARAB9AKMT2AHDAC1HDAC3 | |
| SCHEMBL9901469 | 0.86 | CETP (0.67) | LMNARAB9AHDAC1HDAC3HDAC2 | |
| SCHEMBL16010908 | 0.84 | HDAC3 (0.82) | HDAC1HDAC3HDAC2HDAC6HDAC10 | |
| SCHEMBL21665202 | 0.83 | HTT (0.60) | KMT2AGAAHDAC1HDAC3HDAC2 | |
| SCHEMBL7717024 | 0.82 | HDAC3 (0.61) | RAB9AKMT2AGAAHDAC1HDAC3 | |
| SCHEMBL7717055 | 0.82 | HDAC3 (0.61) | RAB9AKMT2AGAAHDAC1HDAC3 | |
| SCHEMBL7719067 | 0.82 | HDAC3 (0.61) | RAB9AKMT2AGAAHDAC1HDAC3 | |
| SCHEMBL3865714 | 0.81 | L3MBTL1 (0.61) | LMNARAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL1066412 | 0.81 | HDAC3 (0.74) | LMNARAB9AKMT2AHDAC1HDAC3 | |
| SCHEMBL469447 | 0.81 | SMN1; SMN2 (0.65) | RAB9AKMT2AGAAHDAC1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2994122-A1 | NOVEL TRANSCRIPTION FACTOR MODULATORS | C & C Biopharma, LLC (US) | 2016-03-16 | — | — | EP | disclosed |
| US-9133105-B2 | Transcription factor modulators | C&C BIOPHARMA, LLC (US) | 2015-09-15 | — | — | US | disclosed |
| US-9133105-B2 | Transcription factor modulators | C&C BIOPHARMA, LLC (US) | 2015-09-15 | — | — | US | disclosed |
| US-9133105-B2 | Transcription factor modulators | C&C BIOPHARMA, LLC (US) | 2015-09-15 | — | — | US | disclosed |
| WO-2014138508-A1 | NOVEL TRANSCRIPTION FACTOR MODULATORS | C & C BIOPHARMA, LLC (US) | 2014-09-12 | — | — | WO | disclosed |
| WO-2014138508-A1 | NOVEL TRANSCRIPTION FACTOR MODULATORS | C & C BIOPHARMA, LLC (US) | 2014-09-12 | — | — | WO | disclosed |
| US-20140256775-A1 | NOVEL TRANSCRIPTION FACTOR MODULATORS | C & C BIOPHARMA LLC (US) | 2014-09-11 | — | — | US | disclosed |
| US-20140256775-A1 | NOVEL TRANSCRIPTION FACTOR MODULATORS | C & C BIOPHARMA LLC (US) | 2014-09-11 | — | — | US | disclosed |
| US-20140256775-A1 | NOVEL TRANSCRIPTION FACTOR MODULATORS | C & C BIOPHARMA LLC (US) | 2014-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256775-A1 | NOVEL TRANSCRIPTION FACTOR MODULATORS | RELA, CBFB, CREBBP | LMNA 2840/4885RAB9A 4390/4885KMT2A 873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.