Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.32 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16011008 | 1.00 | DPP4 (0.39) | DPP4HRH3FPR2HRH4TIPARP | |
| SCHEMBL16011133 | 0.88 | DPP4 (0.40) | DPP4FPR2 | |
| SCHEMBL16011095 | 0.84 | DPP4 (0.39) | DPP4HRH3 | |
| SCHEMBL14918167 | 0.84 | DPP4 (0.39) | DPP4HRH3 | |
| SCHEMBL16011093 | 0.84 | DPP4 (0.39) | DPP4HRH3 | |
| SCHEMBL14918289 | 0.83 | FPR2 (0.41) | DPP4FPR2 | |
| SCHEMBL14917986 | 0.83 | DPP4 (0.36) | DPP4HRH3FPR2TIPARP | |
| SCHEMBL14917988 | 0.83 | DPP4 (0.36) | DPP4HRH3FPR2TIPARP | |
| SCHEMBL14918213 | 0.80 | FPR2 (0.40) | DPP4HRH3FPR2TIPARP | |
| SCHEMBL16011236 | 0.80 | DPP4 (0.35) | DPP4TIPARP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140256756-A1 | PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS | ARRAY BIOPHARMA, INC. | 2014-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256756-A1 | PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS | GPR119, GPR139, GLP1R | DPP4 567/4885HRH3 323/4885FPR2 142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.