Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1599512 | 0.99 | ALOX15 (0.39) | ALOX15FFAR4MEN1KMT2ASLC6A4 | |
| SCHEMBL1600303 | 0.99 | ALOX15 (0.39) | ALOX15FFAR4MEN1KMT2ASLC6A4 | |
| SCHEMBL1600369 | 0.86 | SLC6A4 (0.34) | MEN1KMT2ASLC6A4SLC6A3SLC6A2 | |
| SCHEMBL1601207 | 0.85 | SLC6A4 (0.36) | MEN1KMT2ASLC6A4SLC6A3SLC6A2 | |
| SCHEMBL3949919 | 0.85 | SLC6A4 (0.36) | MEN1KMT2ASLC6A4SLC6A3SLC6A2 | |
| SCHEMBL4740617 | 0.83 | FFAR4 (0.42) | FFAR4MEN1KMT2A | |
| Benzene SCHEMBL28081456 | 0.83 | SLC6A4 (0.37) | MEN1KMT2ASLC6A4SLC6A3SLC6A2 | |
| SCHEMBL1599597 | 0.79 | TACR1 (0.46) | FFAR4 | |
| SCHEMBL1600514 | 0.78 | IDO1 (0.33) | MEN1KMT2ASLC6A4SLC6A3SLC6A2 | |
| SCHEMBL1600377 | 0.78 | TACR1 (0.42) | SLC6A4SLC6A3CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7919506-B2 | Dibenzyl amine compounds and derivatives | PFIZER INC. (US) | 2011-04-05 | — | — | US | disclosed |
| US-20070213371-A1 | Dibenzyl Amine Compounds and Derivatives | PFIZER INC | 2007-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213371-A1 | Dibenzyl Amine Compounds and Derivatives | APOB, LDLR, CETP | ALOX15 758/4885FFAR4 797/4885MEN1 1597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.