Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11740011 | 0.98 | ACHE (0.57) | ACHEALDH1A1SMN1; SMN2EPHX2EPHX1 | |
| SCHEMBL11736597 | 0.89 | ACHE (0.57) | ACHEALDH1A1SMN1; SMN2EPHX2EPHX1 | |
| SCHEMBL11735248 | 0.87 | ACHE (0.57) | ACHEALDH1A1SMN1; SMN2EPHX2EPHX1 | |
| SCHEMBL29250463 | 0.81 | ACHE (0.68) | ACHEEPHX2EPHX1 | |
| SCHEMBL28370366 | 0.81 | ACHE (0.70) | ACHEEPHX2EPHX1 | |
| SCHEMBL20887861 | 0.81 | ACHE (0.49) | ACHEEPHX2EPHX1 | |
| SCHEMBL8155554 | 0.80 | ACHE (0.52) | ACHEALDH1A1SMN1; SMN2EPHX1 | |
| SCHEMBL8155852 | 0.80 | ACHE (0.52) | ACHEALDH1A1SMN1; SMN2EPHX1 | |
| SCHEMBL22381282 | 0.80 | ACHE (0.66) | ACHEEPHX1 | |
| SCHEMBL15618279 | 0.80 | EPHX2 (0.57) | ACHEEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2964224-B1 | POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT | POLYACTIVA PTY LTD (AU) | 2024-07-03 | — | — | EP | disclosed |
| US-10113033-B2 | Polymer conjugate for delivery of a bioactive agent | POLYACTIVA PTY LTD (AU) | 2018-10-30 | — | — | US | disclosed |
| US-10111886-B2 | Polymer conjugate for delivery of a bioactive agent | POLYACTIVA PTY LTD (AU) | 2018-10-30 | — | — | US | disclosed |
| US-20170216308-A1 | POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT | POLYACTIVA PTY LTD (AU) | 2017-08-03 | — | — | US | disclosed |
| US-20170182173-A1 | POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT | POLYACTIVA PTY LTD (AU) | 2017-06-29 | — | — | US | disclosed |
| US-9572892-B2 | Polymer conjugate for delivery of a bioactive agent | POLYACTIVA PTY LTD (AU) | 2017-02-21 | — | — | US | disclosed |
| EP-2964224-A1 | POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT | Polyactiva Pty Ltd (AU) | 2016-01-13 | — | — | EP | disclosed |
| US-20160000929-A1 | POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT | POLYACTIVA PTY LTD (AU) | 2016-01-07 | — | — | US | disclosed |
| WO-2014134689-A1 | POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT | POLYACTIVA PTY LTD (AU) | 2014-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10113033-B2 | Polymer conjugate for delivery of a bioactive agent | PTGIS, PTGIR, PGF | ACHE 1848/4885ALDH1A1 1479/4885SMN1; SMN2 4706/4885 |
| US-10111886-B2 | Polymer conjugate for delivery of a bioactive agent | PTGIS, PTGIR, PGF | ACHE 797/4885ALDH1A1 1738/4885SMN1; SMN2 4732/4885 |
| US-20160000929-A1 | POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT | PTGIS, PTGIR, PGF | ACHE 939/4885ALDH1A1 1399/4885SMN1; SMN2 4749/4885 |
| US-20170216308-A1 | POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT | PTGIS, PTGIR, PGF | ACHE 797/4885ALDH1A1 1738/4885SMN1; SMN2 4732/4885 |
| US-20170182173-A1 | POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT | PTGIS, PTGIR, PGF | ACHE 1848/4885ALDH1A1 1479/4885SMN1; SMN2 4706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.