Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12124049 | 0.89 | SLC6A3 (0.46) | ALDH1A1SLC6A3SLC6A2SLC6A4GAA | |
| SCHEMBL1334070 | 0.89 | SLC6A3 (0.46) | ALDH1A1SLC6A3SLC6A2SLC6A4GAA | |
| SCHEMBL16015132 | 0.89 | POLB (0.52) | ALDH1A1LMNAPOLBLIPETSHR | |
| SCHEMBL16015140 | 0.86 | LIPE (0.44) | ALDH1A1GAALIPESMN1; SMN2TSHR | |
| SCHEMBL16015146 | 0.85 | LIPE (0.43) | SLC6A3SLC6A2SLC6A4LIPESMN1; SMN2 | |
| SCHEMBL16015137 | 0.85 | TSHR (0.51) | ALDH1A1GAALMNAPOLBLIPE | |
| SCHEMBL16015131 | 0.84 | LIPE (0.46) | ALDH1A1LMNALIPESMN1; SMN2TSHR | |
| SCHEMBL16015134 | 0.83 | LIPE (0.44) | LIPESMN1; SMN2TSHRNPC1RAB9A | |
| SCHEMBL1335621 | 0.82 | LIPE (0.44) | ALDH1A1LIPESMN1; SMN2TSHRNPC1 | |
| SCHEMBL12124090 | 0.82 | LIPE (0.44) | ALDH1A1LIPESMN1; SMN2TSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8829027-B2 | Urea derivatives of substituted nortropanes, medicaments containing such compounds and their use | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-09-09 | — | — | US | disclosed |