Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | SSTR3 | P32745 | 3/20 | 0.51 |
| ▸ | CCR2 | P41597 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.43 |
| ▸ | MLYCD | O95822 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13964104 | 1.00 | RAB9A (0.52) | RAB9ANPC1CYP1A2HPGDCYP2C19 | |
| SCHEMBL12348733 | 0.80 | PRCP (0.46) | HTR2CHTR2B | |
| SCHEMBL16015169 | 0.80 | PRCP (0.46) | HTR2CHTR2B | |
| SCHEMBL28565006 | 0.75 | RAB9A (0.56) | RAB9ANPC1CYP1A2HPGDCYP2C19 | |
| SCHEMBL13927734 | 0.75 | TAS1R3 (0.72) | RAB9ANPC1CYP1A2HPGDCYP2C19 | |
| SCHEMBL4175029 | 0.75 | TAS1R3 (0.72) | RAB9ANPC1CYP1A2HPGDCYP2C19 | |
| SCHEMBL29933088 | 0.75 | RAB9A (0.64) | RAB9ANPC1CYP1A2HPGDCYP2C19 | |
| SCHEMBL13927736 | 0.75 | TAS1R3 (0.72) | RAB9ANPC1CYP1A2HPGDCYP2C19 | |
| SCHEMBL28322880 | 0.74 | MEN1 (0.54) | RAB9ANPC1CYP1A2HPGDCYP2C19 | |
| SCHEMBL28564491 | 0.74 | RAB9A (0.59) | RAB9ANPC1CYP1A2HPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8829208-B2 | Process for the preparation of darunavir and darunavir intermediates | MAPI PHARMA LTD. (IL) | 2014-09-09 | — | — | US | disclosed |
| US-8829208-B2 | Process for the preparation of darunavir and darunavir intermediates | MAPI PHARMA LTD. (IL) | 2014-09-09 | — | — | US | disclosed |