Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PTPRA | P18433 | 1/20 | 0.38 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4666803 | 0.82 | MTNR1A (0.41) | MTNR1AMTNR1BCYP1A2CYP2D6HSD17B10 | |
| SCHEMBL7254438 | 0.82 | MTNR1A (0.41) | MTNR1AMTNR1BCYP1A2CYP2D6HSD17B10 | |
| SCHEMBL4666793 | 0.82 | MTNR1A (0.41) | MTNR1AMTNR1BCYP1A2CYP2D6HSD17B10 | |
| SCHEMBL4666799 | 0.82 | MTNR1A (0.41) | MTNR1AMTNR1BCYP1A2CYP2D6HSD17B10 | |
| SCHEMBL10622948 | 0.79 | LMNA (0.38) | MTNR1AMTNR1BCYP1A2CYP2D6HSD17B10 | |
| SCHEMBL14837249 | 0.77 | KDM1A (0.39) | MTNR1AMTNR1BCYP1A2CYP2D6HSD17B10 | |
| SCHEMBL12512023 | 0.76 | SMN1; SMN2 (0.45) | MTNR1AMTNR1BCYP1A2CYP2D6HSD17B10 | |
| SCHEMBL1859897 | 0.74 | HPGD (0.46) | CYP1A2TSHRALDH1A1MEN1HPGD | |
| SCHEMBL9723648 | 0.74 | HTR2A (0.47) | — | |
| SCHEMBL11313778 | 0.73 | CYP1A2 (0.50) | MTNR1AMTNR1BCYP1A2CYP2D6HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE45128-E1 | Cephalotaxane derivatives and their processes of preparation and purification | IVAX International GmbH (CH) | 2014-09-09 | — | — | US | disclosed |