SCHEMBL9723648

SCHEMBL9723648

C/C(=C/CC(C)N)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 3/20 0.47
MAOA P21397 2/20 0.41
SLC6A2 P23975 2/20 0.41
TAAR1 Q96RJ0 2/20 0.41
SLC6A4 P31645 1/20 0.41
SLC6A3 Q01959 1/20 0.41
SIGMAR1 Q99720 1/20 0.41
CYP2A6 P11509 1/20 0.41
ADORA2A P29274 1/20 0.41
ADORA1 P30542 1/20 0.41
KDM1A O60341 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14837249 0.84 KDM1A (0.39) KDM1A
SCHEMBL10622948 0.82 LMNA (0.38) KDM1A
SCHEMBL1833125 0.81 KDM1A (0.39) HTR2AKDM1A
SCHEMBL1833121 0.81 KDM1A (0.39) HTR2AKDM1A
SCHEMBL1833126 0.81 KDM1A (0.39) HTR2AKDM1A
SCHEMBL8004815 0.81 F2 (0.40) HTR2AMAOA
SCHEMBL5199056 0.80 TBXAS1 (0.51) SLC6A4SLC6A3
SCHEMBL10428568 0.80 IDO1 (0.39) HTR2A
SCHEMBL4666803 0.78 MTNR1A (0.41) HTR2A
SCHEMBL4666793 0.78 MTNR1A (0.41) HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5112924-A Multilayer fabric, fiber or particle composite of improved heat resistance and high strength HERCULES INCORPORATED (US) 1992-05-12 US disclosed
US-5096766-A Prepregs HERCULES INCORPORATED (US) 1992-03-17 US disclosed