Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 6/20 | 0.41 |
| ▸ | CDK2 | P24941 | 6/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16017303 | 0.87 | MEN1 (0.50) | HPGDALDH1A1CCNE1CDK2MAPT | |
| SCHEMBL14879755 | 0.84 | PTGS2 (0.42) | HPGDCCNE1CDK2HIF1AMAPT | |
| SCHEMBL16017352 | 0.80 | ALDH1A1 (0.41) | HPGDALDH1A1MAPTGAAKDM4E | |
| SCHEMBL16017301 | 0.77 | ALDH1A1 (0.43) | HPGDALDH1A1CCNE1CDK2MAPT | |
| SCHEMBL16017439 | 0.74 | ALDH1A1 (0.43) | HPGDALDH1A1CCNE1CDK2MAPT | |
| SCHEMBL16017305 | 0.74 | ALDH1A1 (0.43) | HPGDALDH1A1CCNE1CDK2MAPT | |
| SCHEMBL14887600 | 0.74 | MEN1 (0.47) | HPGDALDH1A1CCNE1CDK2MAPT | |
| SCHEMBL14226018 | 0.73 | PFKFB3 (0.44) | ALDH1A1MAPTLMNAGAAKDM4E | |
| SCHEMBL14879654 | 0.73 | MEN1 (0.46) | HPGDALDH1A1CCNE1CDK2MAPT | |
| SCHEMBL11510867 | 0.72 | MAPT (0.68) | HPGDALDH1A1CCNE1CDK2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140256771-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA, INC. | 2014-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256771-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | ORAI1, SARAF, RYR2 | HPGD 1883/4885ALDH1A1 4409/4885CCNE1 4315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.