Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 2/20 | 0.50 |
| ▸ | FLT3 | P36888 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMO | O15229 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3105981 | 0.77 | KMT2A (0.49) | KDM4EALDH1A1SIGMAR1TSHRKCNH2 | |
| Hydrochloric Acid SCHEMBL9013588 | 0.74 | NPC1 (0.55) | NPC1 | |
| SCHEMBL3716249 | 0.74 | SMN1; SMN2 (0.47) | KDM4EALDH1A1SIGMAR1TSHRKCNH2 | |
| SCHEMBL3205812 | 0.73 | KDM4E (0.52) | KDM4EALDH1A1SIGMAR1TSHRKMO | |
| SCHEMBL1602724 | 0.72 | PIKFYVE (0.55) | KITFLT3ROCK2ROCK1KDM4E | |
| Hydrochloric Acid SCHEMBL9013522 | 0.72 | ESR1 (0.53) | ESR1 | |
| SCHEMBL30986449 | 0.71 | KDM4E (0.56) | KDM4EALDH1A1SIGMAR1TSHRKCNH2 | |
| SCHEMBL11929837 | 0.70 | NPC1 (0.52) | KDM4EALDH1A1SIGMAR1TSHRKCNH2 | |
| SCHEMBL15260226 | 0.70 | KDM4E (0.66) | KDM4EALDH1A1TSHRNPC1 | |
| SCHEMBL247423 | 0.69 | KIT (0.45) | KITFLT3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7919487-B2 | Heteroaryl compounds | SYNTA PHARMACEUTICALS CORPORATION (US) | 2011-04-05 | — | — | US | disclosed |
| US-7919487-B2 | Heteroaryl compounds | SYNTA PHARMACEUTICALS CORPORATION (US) | 2011-04-05 | — | — | US | disclosed |
| US-7919487-B2 | Heteroaryl compounds | SYNTA PHARMACEUTICALS CORPORATION (US) | 2011-04-05 | — | — | US | disclosed |
| US-20060122156-A1 | Heteroaryl compounds | SYNTA PHARMACEUTICALS CORP. (US) | 2006-06-08 | — | — | US | disclosed |
| WO-2006053109-A1 | HETEROARYL COMPOUNDS | SYNTA PHARMACEUTICALS CORP. (US) | 2006-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060122156-A1 | Heteroaryl compounds | IL2, CCL11, IL4 | KIT 376/4885FLT3 332/4885ESR1 3146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.