SCHEMBL16019256

SCHEMBL16019256

Cc1cccc2c(-n3c(=O)c4cc5oc6cc7c(cc6oc5cc4c3=O)C3(CC(C)(C)c4cc5oc6cc8c(=O)n(C)c(=O)c8cc6oc5cc43)CC7(C)C)cccc12

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19075867 0.82
SCHEMBL18053255 0.76
SCHEMBL22808126 0.72
SCHEMBL24285462 0.71 EGFR (0.35)
SCHEMBL24285571 0.69 LMNA (0.32)
SCHEMBL16019261 0.68 KDM4E (0.33)
SCHEMBL12124170 0.68 MAPT (0.35)
SCHEMBL16019263 0.67 MAPT (0.30)
SCHEMBL24285443 0.66
SCHEMBL19084284 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9522364-B2 Treated mixed matrix polymeric membranes SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-12-20 US disclosed
US-9492785-B2 UV and thermally treated polymeric membranes SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-11-15 US disclosed
US-20160263532-A1 ULTRAVIOLET AND PLASMA-TREATED POLYMERIC MEMBRANES SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-09-15 US disclosed
US-20160263531-A1 PLASMA-TREATED POLYMERIC MEMBRANES SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-09-15 US disclosed
US-20160263533-A1 TREATED MIXED MATRIX POLYMERIC MEMBRANES SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-09-15 US disclosed
US-20160250585-A1 UV AND THERMALLY TREATED POLYMERIC MEMBRANES SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-09-01 US disclosed
US-20140255636-A1 Polymeric Membranes SAUDI BASIC INDUSTRIES CORPORATION (SA) 2014-09-11 US disclosed