SCHEMBL12124170

SCHEMBL12124170

CC1(C)CC2(CC(C)(C)c3cc4oc5cc6c(=O)oc(=O)c6cc5oc4cc32)c2cc3oc4cc5c(=O)oc(=O)c5cc4oc3cc21

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.35
KDM4E B2RXH2 3/20 0.35
ALDH1A1 P00352 3/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
POLB P06746 1/20 0.35
STAT1 P42224 1/20 0.35
HPGD P15428 1/20 0.31
CASP3 P42574 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
SENP8 Q96LD8 1/20 0.31
SENP7 Q9BQF6 1/20 0.31
SENP6 Q9GZR1 1/20 0.31
LMNA P02545 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19075867 0.83
SCHEMBL17552915 0.78 RARB (0.38)
SCHEMBL12124171 0.77
SCHEMBL13250931 0.76 KDM4E (0.39) MAPTKDM4EALDH1A1NPC1RAB9A
SCHEMBL17320626 0.73 PDE2A (0.41) MAPTKDM4EALDH1A1NPC1RAB9A
SCHEMBL24285571 0.72 LMNA (0.32) MAPTLMNA
SCHEMBL15086100 0.71
SCHEMBL24285462 0.69 EGFR (0.35) LMNA
SCHEMBL807580 0.68 ALDH1A1 (0.34) ALDH1A1
SCHEMBL11136773 0.65 CA12 (0.41) MAPTKDM4EALDH1A1SMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230178848-A1 ELECTRODE SEPARATORS UNIV KING ABDULLAH SCI & TECH (SA) 2023-06-08 US disclosed
US-20230178848-A1 ELECTRODE SEPARATORS UNIV KING ABDULLAH SCI & TECH (SA) 2023-06-08 US disclosed
EP-3985439-B1 MATERIAL FOR FORMING ORGANIC FILM, SUBSTRATE FOR MANUFACTURING SEMICONDUCTOR DEVICE, METHOD FOR FORMING ORGANIC FILM, PATTERNING PROCESS, AND COMPOUND FOR FORMING ORGANIC FILM SHINETSU CHEMICAL CO (JP) 2023-02-15 EP disclosed
US-20220219125-A1 HYBRID INORGANIC OXIDE-CARBON MOLECULAR SIEVE MEMBRANES UNIV KING ABDULLAH SCI & TECH (SA) 2022-07-14 US disclosed
EP-3985439-A1 MATERIAL FOR FORMING ORGANIC FILM, SUBSTRATE FOR MANUFACTURING SEMICONDUCTOR DEVICE, METHOD FOR FORMING ORGANIC FILM, PATTERNING PROCESS, AND COMPOUND FOR FORMING ORGANIC FILM Shin-Etsu Chemical Co., Ltd. (JP) 2022-04-20 EP disclosed
US-10961349-B2 O-hydroxy-functionalized diamines, polyimides, methods of making each, and methods of use KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) 2021-03-30 US disclosed
EP-3533781-A1 O-HYDROXY-FUNCTIONALIZED DIAMINES, POLYMIDES, METHODS OF MAKING EACH, AND METHODS OF USE King Abdullah University Of Science And Technology (SA) 2019-09-04 EP disclosed
US-20190218345-A1 O-HYDROXY-FUNCTIONALIZED DIAMINES, POLYIMIDES, METHODS OF MAKING EACH, AND METHODS OF USE UNIV KING ABDULLAH SCI & TECH (SA) 2019-07-18 US disclosed
EP-3169661-B1 O-HYDROXY-FUNCTIONALIZED DIAMINES, POLYMIDES, METHODS OF MAKING EACH, AND METHODS OF USE UNIV KING ABDULLAH SCI & TECH (SA) 2019-06-19 EP disclosed
US-10240001-B2 O-hydroxy-functionalized diamines, polyimides, methods of making each, and methods of use KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) 2019-03-26 US disclosed
US-20170190842-A1 O-HYDROXY-FUNCTIONALIZED DIAMINES, POLYIMIDES, METHODS OF MAKING EACH, AND METHODS OF USE KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) 2017-07-06 US disclosed
US-20160367948-A1 CROSSLINKED POLYMER, METHOD FOR PRODUCING THE SAME, MOLECULAR SIEVE COMPOSITION AND MATERIAL SEPARATION MEMBRANES KYOTO UNIVERSITY (JP) 2016-12-22 US disclosed
US-20160367948-A1 CROSSLINKED POLYMER, METHOD FOR PRODUCING THE SAME, MOLECULAR SIEVE COMPOSITION AND MATERIAL SEPARATION MEMBRANES KYOTO UNIVERSITY (JP) 2016-12-22 US disclosed
WO-2016009273-A2 O-HYDROXY-FUNCTIONALIZED DIAMINES, POLYMIDES, METHODS OF MAKING EACH, AND METHODS OF USE KING ABDULLAH UNIVERSITY OF SCIENCES AND TECHNOLOGY (SA) 2016-01-21 WO disclosed
US-8056732-B2 Microporous polymer material THE UNIVERSITY OF MANCHESTER (GB) 2011-11-15 US disclosed
US-8056732-B2 Microporous polymer material THE UNIVERSITY OF MANCHESTER (GB) 2011-11-15 US disclosed
US-20100304112-A1 MICROPOROUS POLYMER MATERIAL THE UNIVERSITY OF MANCHESTER (GB) 2010-12-02 US disclosed
US-20100304112-A1 MICROPOROUS POLYMER MATERIAL THE UNIVERSITY OF MANCHESTER (GB) 2010-12-02 US disclosed
US-7690514-B2 Microporous polymer material THE UNIVERSITY OF MANCHESTER (GB) 2010-04-06 US disclosed
US-7690514-B2 Microporous polymer material THE UNIVERSITY OF MANCHESTER (GB) 2010-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10961349-B2 O-hydroxy-functionalized diamines, polyimides, methods of making each, and methods of use ALKBH3, AOC1, PAM MAPT 3676/4885KDM4E 320/4885ALDH1A1 540/4885
US-20190218345-A1 O-HYDROXY-FUNCTIONALIZED DIAMINES, POLYIMIDES, METHODS OF MAKING EACH, AND METHODS OF USE ALKBH3, AOC1, PAM MAPT 3676/4885KDM4E 320/4885ALDH1A1 540/4885
US-20170190842-A1 O-HYDROXY-FUNCTIONALIZED DIAMINES, POLYIMIDES, METHODS OF MAKING EACH, AND METHODS OF USE ALKBH3, AOC1, PAM MAPT 3676/4885KDM4E 320/4885ALDH1A1 540/4885
US-10240001-B2 O-hydroxy-functionalized diamines, polyimides, methods of making each, and methods of use ALKBH3, AOC1, PAM MAPT 3676/4885KDM4E 320/4885ALDH1A1 540/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.