Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PLEC | Q15149 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20854323 | 0.92 | ABCB1 (0.54) | USP2L3MBTL1ABCB1KDM4EALDH1A1 | |
| SCHEMBL16019280 | 0.91 | USP2 (0.52) | USP2L3MBTL1ABCB1KDM4EALDH1A1 | |
| SCHEMBL28520428 | 0.84 | ABCB1 (0.48) | USP2L3MBTL1ABCB1KDM4EALDH1A1 | |
| SCHEMBL30125078 | 0.82 | USP2 (0.49) | USP2L3MBTL1ABCB1ATMMEN1 | |
| SCHEMBL1104941 | 0.82 | USP2 (0.49) | USP2L3MBTL1ABCB1ATMMEN1 | |
| SCHEMBL10205410 | 0.82 | ABCB1 (0.48) | USP2L3MBTL1ABCB1KDM4EALDH1A1 | |
| SCHEMBL30887191 | 0.81 | USP2 (0.44) | USP2L3MBTL1ABCB1KDM4EALDH1A1 | |
| SCHEMBL3872337 | 0.81 | USP2 (0.44) | USP2L3MBTL1ABCB1KDM4EALDH1A1 | |
| SCHEMBL14008329 | 0.81 | KDM4E (0.50) | USP2L3MBTL1ABCB1KDM4EALDH1A1 | |
| SCHEMBL14008331 | 0.81 | KDM4E (0.48) | USP2L3MBTL1ABCB1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052529-B1 | SINGLE-STEP FUNCTIONALIZATION AND CROSS-LINKING OF HYALURONIC ACID | GALDERMA SA (CH) | 2017-10-04 | — | — | EP | disclosed |
| US-20160237177-A1 | SINGLE-STEP FUNCTIONALIZATION AND CROSS-LINKING OF HYALURONIC ACID | GALDERMA S.A. (CH) | 2016-08-18 | — | — | US | disclosed |
| US-20160237177-A1 | SINGLE-STEP FUNCTIONALIZATION AND CROSS-LINKING OF HYALURONIC ACID | GALDERMA S.A. (CH) | 2016-08-18 | — | — | US | disclosed |
| WO-2015044455-A1 | SINGLE-STEP FUNCTIONALIZATION AND CROSS-LINKING OF HYALURONIC ACID | GALDERMA S.A. (CH) | 2015-04-02 | — | — | WO | disclosed |
| US-20140256015-A1 | CAGED COMPOUND WHICH CAN BE PHOTOACTIVATED SELECTIVELY FOR CELL TYPES | TOHO UNIVERSITY (JP) | 2014-09-11 | — | — | US | disclosed |
| US-20140256015-A1 | CAGED COMPOUND WHICH CAN BE PHOTOACTIVATED SELECTIVELY FOR CELL TYPES | TOHO UNIVERSITY (JP) | 2014-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160237177-A1 | SINGLE-STEP FUNCTIONALIZATION AND CROSS-LINKING OF HYALURONIC ACID | CD44, HAO2, HAO1 | USP2 724/4885L3MBTL1 4748/4885ABCB1 2690/4885 |
| US-20140256015-A1 | CAGED COMPOUND WHICH CAN BE PHOTOACTIVATED SELECTIVELY FOR CELL TYPES | CTSK, CTSF, TPX2 | USP2 1436/4885L3MBTL1 3117/4885ABCB1 3584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.