Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16017904 | 0.83 | CYP1A2 (0.40) | — | |
| SCHEMBL16021175 | 0.80 | L3MBTL1 (0.34) | L3MBTL1KMT2APOLB | |
| SCHEMBL16017768 | 0.77 | PRKCA (0.36) | POLB | |
| SCHEMBL16017782 | 0.75 | PRKCA (0.34) | — | |
| SCHEMBL16017854 | 0.70 | ADRA2A (0.39) | KMT2A | |
| Bis(Pivaloyloxymethyl) Succinate SCHEMBL3123390 | 0.70 | PRKCA (0.41) | POLB | |
| SCHEMBL16017788 | 0.68 | ADRA2A (0.36) | POLB | |
| SCHEMBL16019101 | 0.68 | ADRA2A (0.36) | POLB | |
| SCHEMBL16019104 | 0.68 | ADRA2A (0.36) | POLB | |
| SCHEMBL16019103 | 0.68 | HTR2C (0.41) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140256651-A1 | Cyclosporine A steroid conjugates | ALLERGAN, INC. (US) | 2014-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256651-A1 | Cyclosporine A steroid conjugates | CYP21A2, CHP1, CYP51A1 | L3MBTL1 4857/4885KMT2A 4464/4885POLB 2708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.