Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 5/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MLYCD | O95822 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 5/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.32 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13677362 | 0.82 | POLB (0.43) | ESR1ESR2LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL13104238 | 0.82 | POLB (0.43) | ESR1ESR2LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL469235 | 0.82 | POLB (0.43) | ESR1ESR2LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL26803183 | 0.81 | MLYCD (0.35) | RORCESR1ESR2LMNASMN1; SMN2 | |
| SCHEMBL18745852 | 0.80 | NPC1 (0.35) | NPC1RAB9ALMNAMAPK1CASP3 | |
| SCHEMBL26802057 | 0.79 | ESR1 (0.35) | RORCESR1ESR2MLYCD | |
| SCHEMBL14138090 | 0.74 | RORC (0.30) | RORC | |
| SCHEMBL12692496 | 0.73 | CCR1 (0.43) | ESR1ESR2RAB9AMAPTTDP1 | |
| SCHEMBL12295857 | 0.73 | NPC1 (0.39) | NPC1RAB9ALMNAMAPK1CASP3 | |
| SCHEMBL17433153 | 0.73 | NPC1 (0.39) | NPC1RAB9ALMNAMAPK1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3207043-B3 | DIHYDROPYRROLOPYRIDINE INHIBITORS OF ROR-GAMMA | VITAE PHARMACEUTICALS LLC (US) | 2019-10-02 | — | — | EP | disclosed |
| US-20140251407-A1 | THERMOELECTRIC CONVERSION MATERIAL AND A THERMOELECTRIC CONVERSION ELEMENT | FUJIFILM CORPORATION (JP) | 2014-09-11 | — | — | US | disclosed |