SCHEMBL17433153

SCHEMBL17433153

CCC(C)(C)c1ccc(C(C)(C)CC)nc1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
MAPT P10636 1/20 0.39
LMNA P02545 1/20 0.37
MAPK1 P28482 1/20 0.37
CASP3 P42574 1/20 0.37
ATM Q13315 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
SENP8 Q96LD8 1/20 0.37
SENP7 Q9BQF6 1/20 0.37
SENP6 Q9GZR1 1/20 0.37
HRH3 Q9Y5N1 12/20 0.35
MAOB P27338 8/20 0.35
TDP1 Q9NUW8 1/20 0.33
KDM2B Q8NHM5 1/20 0.33
PTPN1 P18031 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13751317 0.90 NPC1 (0.38) NPC1RAB9AMAPTLMNAMAPK1
SCHEMBL15499726 0.90 LOXL2 (0.36) NPC1RAB9AMAPTLMNAMAPK1
SCHEMBL18869960 0.86 HPGD (0.42) NPC1RAB9AMAPK1SMN1; SMN2
SCHEMBL19388193 0.86 TRPV4 (0.47) NPC1RAB9AMAPTLMNAMAPK1
SCHEMBL12045147 0.86 NPC1 (0.36) NPC1RAB9AMAPTLMNAMAPK1
SCHEMBL12295857 0.79 NPC1 (0.39) NPC1RAB9AMAPTLMNAMAPK1
SCHEMBL17403395 0.79 TRPV4 (0.52)
SCHEMBL217684 0.79 CCR1 (0.43) RAB9AMAPT
SCHEMBL12928308 0.78 ALOX5AP (0.35) NPC1RAB9ALMNAMAPK1CASP3
SCHEMBL23660556 0.78 NPC1 (0.38) NPC1RAB9AMAPTLMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10336860-B2 Polymer compound and light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-07-02 US disclosed
US-20170283546-A1 POLYMER COMPOUND AND LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-10-05 US disclosed
US-20170200563-A1 MODULATING ELECTRON TRANSFER DYNAMICS AT HYBRID INTERFACES VIA SELF-ASSEMBLED MULTILAYERS UNIV FLORIDA STATE RES FOUND (US) 2017-07-13 US disclosed
US-20170125832-A1 POLYMER ELECTROLYTE COMPOSITION AND POLYMER ELECTROLYTE MEMBRANE, POLYMER ELECTROLYTE MEMBRANE WITH CATALYST LAYER, MEMBRANE ELECTRODE ASSEMBLY, AND POLYMER ELECTROLYTE FUEL CELL EACH USING THE SAME TORAY INDUSTRIES, INC. (JP) 2017-05-04 US disclosed
US-20160013392-A1 METHOD OF PRODUCING THERMOELECTRIC CONVERSION ELEMENT AND METHOD OF PREPARATION DISPERSION FOR THERMOELECTRIC CONVERSION LAYER FUJIFILM CORPORATION (JP) 2016-01-14 US disclosed