Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.50 |
| ▸ | CSF1R | P07333 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14970191 | 0.87 | NPC1 (0.55) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL20503069 | 0.87 | KDM4E (0.55) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL20503074 | 0.87 | PDE4D (0.60) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL19377733 | 0.85 | ALDH1A1 (0.50) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL17429964 | 0.84 | PDE4A (0.55) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL17430371 | 0.84 | HTT (0.43) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL17430272 | 0.83 | NPSR1 (0.56) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL248654 | 0.81 | GSK3A (0.47) | ALDH1A1KDM4EHPGDMAPTGAA | |
| SCHEMBL17430381 | 0.81 | SMN1; SMN2 (0.44) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL20503072 | 0.79 | MAPT (0.52) | ALDH1A1KDM4EHSD17B10HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10081608-B2 | 6-acyl-1,2,4-triazine-3,5-dione derivative and herbicides | FMC CORPORATION (US) | 2018-09-25 | — | — | US | disclosed |
| US-20160009693-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2016-01-14 | — | — | US | disclosed |
| US-20160009693-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2016-01-14 | — | — | US | disclosed |
| WO-2014135654-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2014-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10081608-B2 | 6-acyl-1,2,4-triazine-3,5-dione derivative and herbicides | DDT, AADAC, DAZAP1 | ALDH1A1 144/4885KDM4E 900/4885HSD17B10 230/4885 |
| US-20160009693-A1 | HERBICIDAL COMPOUNDS | DDT, HAX1, CYP4X1 | ALDH1A1 79/4885KDM4E 1632/4885HSD17B10 228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.