Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17427363 | 0.86 | RAB9A (0.42) | SMN1; SMN2RAB9ANPC1PKML3MBTL1 | |
| SCHEMBL14970191 | 0.81 | NPC1 (0.55) | SMN1; SMN2RAB9ANPC1L3MBTL1ALDH1A1 | |
| SCHEMBL20503069 | 0.81 | KDM4E (0.55) | SMN1; SMN2RAB9ANPC1L3MBTL1ALDH1A1 | |
| SCHEMBL16021998 | 0.81 | ALDH1A1 (0.54) | RAB9ANPC1ALDH1A1HPGDHTT | |
| SCHEMBL17430373 | 0.79 | OXTR (0.42) | SMN1; SMN2RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL17430371 | 0.78 | HTT (0.43) | SMN1; SMN2RAB9ANPC1ALDH1A1POLB | |
| SCHEMBL16022006 | 0.77 | POLB (0.39) | SMN1; SMN2RAB9ANPC1PKML3MBTL1 | |
| SCHEMBL16163687 | 0.76 | MAPT (0.61) | SMN1; SMN2RAB9APKML3MBTL1ALDH1A1 | |
| SCHEMBL16163479 | 0.75 | MAPT (0.57) | SMN1; SMN2PKML3MBTL1ALDH1A1TDP1 | |
| SCHEMBL16163911 | 0.75 | MAPT (0.57) | SMN1; SMN2PKML3MBTL1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160009693-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2016-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160009693-A1 | HERBICIDAL COMPOUNDS | DDT, HAX1, CYP4X1 | SMN1; SMN2 4026/4885RAB9A 2062/4885NPC1 4146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.