Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.73 |
| ▸ | THRB | P10828 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.50 |
| ▸ | CES2 | O00748 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexadecane SCHEMBL3840074 | 1.00 | TSHR (0.73) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| Dodecane SCHEMBL1822133 | 1.00 | TSHR (0.73) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| Alcohol SCHEMBL5478963 | 1.00 | TSHR (0.73) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| Decane SCHEMBL8680306 | 1.00 | TSHR (0.73) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| Undecane SCHEMBL20397396 | 1.00 | TSHR (0.73) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| Heptane SCHEMBL23533257 | 1.00 | TSHR (0.73) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| Decane SCHEMBL424890 | 1.00 | TSHR (0.73) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| Heptane SCHEMBL3790328 | 1.00 | TSHR (0.73) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| Dodecane SCHEMBL5574546 | 1.00 | TSHR (0.73) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| Heptane SCHEMBL11152266 | 1.00 | TSHR (0.73) | TSHRTHRBALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023133386-A1 | COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING MUCOSAL TISSUE DAMAGE OR DISEASE | MEBO INTERNATIONAL, INC. (US) | 2023-07-13 | — | — | WO | disclosed |
| CN-109965167-A | A kind of n-octacosanol sports drink and preparation method thereof | 江南大学 | 2019-07-05 | — | — | CN | disclosed |
| CN-109161438-A | A kind of rice bran oil refining method | 山东三星玉米产业科技有限公司 | 2019-01-08 | — | — | CN | disclosed |
| CN-108835408-A | A kind of feed addictive and production method containing rice bran extract high-carbon fatty alcohol and plants essential oil | 江苏隆达生物科技有限公司 | 2018-11-20 | — | — | CN | disclosed |
| CN-106420832-A | Preparation method of myricin | 广州白云山医药集团股份有限公司白云山化学制药厂 | 2017-02-22 | — | — | CN | disclosed |
| CN-104450839-A | Preparation method of rice bran protein peptide with ACE inhibitory activity | UNIV HARBIN COMMERCE | 2015-03-25 | — | — | CN | disclosed |
| EP-1439847-B1 | METHOD AND COMPOSITION FOR REPAIRING AND PROMOTING REGENERATION OF MUCOSAL TISSUE IN THE GASTROINTESTINAL TRACT | XU RONGXIANG (US) | 2011-05-25 | — | — | EP | disclosed |
| US-7919123-B2 | Orally administering edible oil homogenized with edible wax and a sterol comprising stigmasterol, campesterol, p-sitosterol, chalinosterol, clionasterol, brassicasterol, alpha -spinasterol, daucosterol, desmosterol, and poriferasterol to treat colorectal, stomach, and/or esophagus cancer | XU RONGXIANG | 2011-04-05 | — | — | US | disclosed |
| CN-100548382-C | Pharmaceutical carrier and preparation method thereof | RONGXIANG XU (CN) | 2009-10-14 | — | — | CN | disclosed |
| CN-100444844-C | Composition for repairing and promoting regeneration of gastrointestinal mucosal tissue and preparation method thereof | RONGXIANG XU (CN) | 2008-12-24 | — | — | CN | disclosed |
| CN-1891302-A | Drug carrier and method for preparing same | XU RONGXIANG (CN) | 2007-01-10 | — | — | CN | disclosed |
| US-20060198898-A1 | Method for Preventing Ulceration or Irritation of Mucosa | XU RONGXIANG | 2006-09-07 | — | — | US | disclosed |
| US-7074438-B2 | Compositions for oral delivery of nutrients and pharmaceuticals | XU RONGXIANG | 2006-07-11 | — | — | US | disclosed |
| EP-1439847-A4 | METHOD AND COMPOSITION FOR REPAIRING AND PROMOTING REGENERATION OF MUCOSAL TISSUE IN THE GASTROINTESTINAL TRACT | XU RONGXIANG (US) | 2005-12-14 | — | — | EP | disclosed |
| EP-1439847-A1 | METHOD AND COMPOSITION FOR REPAIRING AND PROMOTING REGENERATION OF MUCOSAL TISSUE IN THE GASTROINTESTINAL TRACT | Xu, Rongxiang (US) | 2004-07-28 | — | — | EP | disclosed |
| US-20040115243-A1 | Compositions for oral delivery of nutrients and pharmaceuticals | XU RONGXIANG (US) | 2004-06-17 | — | — | US | disclosed |
| US-6685971-B2 | OIL HOMOGENIZED WITH STEROLS; PROTECTIVE COATING FOR STOMACH | Xu, Rongxiang | 2004-02-03 | — | — | US | disclosed |
| US-20030091651-A1 | Method and composition for repairing and promoting regeneration of mucosal tissue in the gastrointestinal tract | XU RONGXIANG (US) | 2003-05-15 | — | — | US | disclosed |
| WO-2003037360-A1 | METHOD AND COMPOSITION FOR REPAIRING AND PROMOTING REGENERATION OF MUCOSAL TISSUE IN THE GASTROINTESTINAL TRACT | XU RONGXIANG (US) | 2003-05-08 | — | — | WO | disclosed |
| CN-1404835-A | Composition for repairing and promoting regeneration of gastrointestinal mucosal tissue and preparation method thereof | XU RONGXIANG (CN) | 2003-03-26 | — | — | CN | disclosed |