Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Dodecane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.73 |
| ▸ | THRB | P10828 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.50 |
| ▸ | CES2 | O00748 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexadecane SCHEMBL3840074 | 1.00 | TSHR (0.73) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| Dodecane SCHEMBL1822133 | 1.00 | TSHR (0.73) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| Alcohol SCHEMBL5478963 | 1.00 | TSHR (0.73) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| Decane SCHEMBL8680306 | 1.00 | TSHR (0.73) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| Alcohol SCHEMBL1602280 | 1.00 | TSHR (0.73) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| Undecane SCHEMBL20397396 | 1.00 | TSHR (0.73) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| Heptane SCHEMBL23533257 | 1.00 | TSHR (0.73) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| Decane SCHEMBL424890 | 1.00 | TSHR (0.73) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| Heptane SCHEMBL3790328 | 1.00 | TSHR (0.73) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| Heptane SCHEMBL11152266 | 1.00 | TSHR (0.73) | TSHRTHRBALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110869355-B | Benzopyran compound, curable composition containing the compound, and optical article containing cured product formed from the curable composition | 株式会社德山 | 2023-11-14 | — | — | CN | disclosed |
| CN-116806229-A | Novel curable composition containing cyclic monomer | 株式会社德山 | 2023-09-26 | — | — | CN | disclosed |
| CN-116745336-A | Curable composition comprising cyclic polyfunctional monomer | 株式会社德山 | 2023-09-12 | — | — | CN | disclosed |
| CN-116745333-A | Novel minute hollow particles formed of melamine resin | 国立大学法人鹿儿岛大学 | 2023-09-12 | — | — | CN | disclosed |
| WO-2022045018-A1 | POLYMERIZABLE FUNCTIONAL GROUP-CONTAINING MICROBALLOON | 株式会社トクヤマ | 2022-03-03 | — | — | WO | disclosed |
| WO-2021241709-A1 | POLYFUNCTIONAL QUATERNARY AMMONIUM SALT OF SULFONIC ACID HAVING ACTIVE-HYDROGEN GROUPS | 株式会社トクヤマ | 2021-12-02 | — | — | WO | disclosed |
| CN-113330058-A | Nucleating agent composition, olefin resin composition, molded article thereof, and method for producing olefin resin composition | 株式会社ADEKA | 2021-08-31 | — | — | CN | disclosed |
| CN-109715693-B | Polymerizable composition for optical material, optical material obtained from the composition, and method for producing the same | 三井化学株式会社 | 2021-07-09 | — | — | CN | disclosed |
| WO-2021065625-A1 | MICROBALLOON PRODUCTION METHOD | 株式会社トクヤマ | 2021-04-08 | — | — | WO | disclosed |
| CN-112424260-A | Photochromic compound and curable composition containing same | 株式会社德山 | 2021-02-26 | — | — | CN | disclosed |
| CN-107835951-A | Photochromic coating composition | 株式会社德山 | 2018-03-23 | — | — | CN | disclosed |
| CN-104335083-B | Polymerizable composition for optical material, the optical material and plastic lens obtained by said composition | 三井化学株式会社 | 2017-11-24 | — | — | CN | disclosed |
| CN-103509516-B | Ultraviolet-curing adhesive resin combination and adhesive | DIC株式会社 | 2017-05-31 | — | — | CN | disclosed |
| CN-106164709-A | Polyisocyanate monomer composition for optical member, and method for producing same | 豪雅镜片泰国有限公司 | 2016-11-23 | — | — | CN | disclosed |
| CN-105934458-A | Polymerizable composition for optical material, optical material obtained from the composition, and plastic lens | 三井化学株式会社 | 2016-09-07 | — | — | CN | disclosed |
| CN-102994036-B | Resin composition for ultraviolet curable adhesive and sticker | DIC株式会社 | 2016-07-27 | — | — | CN | disclosed |
| CN-105683334-A | Photochromic composition | 株式会社德山 | 2016-06-15 | — | — | CN | disclosed |
| CN-104335083-A | Polymerizable composition for optical material, optical material and plastic lens obtained from said composition | MITSU CHEMICALS INC | 2015-02-04 | — | — | CN | disclosed |
| EP-1739462-A1 | POLARIZING PLASTIC OPTICAL DEVICE AND PROCESS FOR PRODUCING THE SAME | Sunlux Co., Ltd. (JP) | 2007-01-03 | — | — | EP | disclosed |
| US-5693738-A | REACTING AN ISOCYANATE AND/OR AN ISOTHIOCYANATE COMPOUND WITH A HYDROXYL AND/OR MERCAPTO-CONTAINING COMPOUND IN THE PRESENCE OF A COMPLEX OF A TERTIARY AMINE AND A LEWIS ACID | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-12-02 | — | — | US | disclosed |