Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Decane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.73 |
| ▸ | THRB | P10828 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.50 |
| ▸ | CES2 | O00748 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexadecane SCHEMBL3840074 | 1.00 | TSHR (0.73) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| Dodecane SCHEMBL1822133 | 1.00 | TSHR (0.73) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| Alcohol SCHEMBL5478963 | 1.00 | TSHR (0.73) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| Decane SCHEMBL8680306 | 1.00 | TSHR (0.73) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| Alcohol SCHEMBL1602280 | 1.00 | TSHR (0.73) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| Undecane SCHEMBL20397396 | 1.00 | TSHR (0.73) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| Heptane SCHEMBL23533257 | 1.00 | TSHR (0.73) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| Heptane SCHEMBL3790328 | 1.00 | TSHR (0.73) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| Dodecane SCHEMBL5574546 | 1.00 | TSHR (0.73) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| Heptane SCHEMBL11152266 | 1.00 | TSHR (0.73) | TSHRTHRBALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111689941-A | Trifluoro sulfonamide 1, 4-dioxospiro [4,5] decane photoresist resin monomer and preparation method thereof | 徐州博康信息化学品有限公司 | 2020-09-22 | — | — | CN | claimed |
| CN-105638371-B | A kind of green propagation method of Gu tea tree | 信阳农林学院 | 2019-01-18 | — | — | CN | claimed |
| CN-102549138-A | Cationic emulsifiers free of petrochemically derived neutral amino acid esters and compositions and methods thereof | INOLEX INVESTMENT CORP | 2012-07-04 | — | — | CN | claimed |
| CN-101423459-A | Synthetic method of tricyclo-decane | SHANGHAI RES INST OF FRAGRANCE (CN) | 2009-05-06 | — | — | CN | claimed |
| CN-100435640-C | Woody plant seed soaking agent | JIANJUN YE (CN) | 2008-11-26 | — | — | CN | claimed |
| CN-101311187-A | Tripterine derivate, preparation method and use thereof | YANTAI TARGET DRUG RES CO LTD (CN) | 2008-11-26 | — | — | CN | claimed |
| CN-1907030-A | Woody plant seed soaking agent | YE JIANJUN (CN) | 2007-02-07 | — | — | CN | claimed |
| US-20240026144-A1 | AQUEOUS DISPERSION OF ACRYLIC URETHANE COMPOSITE RESIN PARTICLES, AQUEOUS COATING COMPOSITION, METHOD OF FORMING COATING FILM, AND METHOD OF FORMING MULTILAYER COATING FILM | KANSAI PAINT CO., LTD. (JP) | 2024-01-25 | — | — | US | disclosed |
| WO-2024018708-A1 | AQUEOUS COATING MATERIAL COMPOSITION, METHOD FOR FORMING COATING FILM, AND METHOD FOR FORMING MULTILAYER COATING FILM | 関西ペイント株式会社 | 2024-01-25 | — | — | WO | disclosed |
| CN-112239209-B | Drug delivery via pore-modified mesoporous silica nanoparticles | 奈力生医股份有限公司 | 2024-01-12 | — | — | CN | disclosed |
| CN-117243839-A | Minoxidil adjuvant therapy | 应用生物学股份有限公司 | 2023-12-19 | — | — | CN | disclosed |
| EP-3766482-B1 | DRUG DELIVERY BY PORE-MODIFIED MESOPOROUS SILICA NANOPARTICLES | NANO TARGETING & THERAPY BIOPHARMA INC (TW) | 2023-11-22 | — | — | EP | disclosed |
| WO-2023181492-A1 | AQUEOUS COATING MATERIAL COMPOSITION AND METHOD FOR FORMING MULTILAYER COATING FILM | 関西ペイント株式会社 | 2023-09-28 | — | — | WO | disclosed |
| CN-1351650-A | Application of microemulsion in fermentation process | COGNIS DEUTSCHLAND GMBH (DE) | 2002-05-29 | — | — | CN | disclosed |
| US-20020016299-A1 | APOPTOSIS INDUCERS | TAKARA BIO INC. (JP) | 2002-02-07 | — | — | US | disclosed |
| CN-1322227-A | Yellow toner compound and aqueous ink for ink-jet recording apparatus using the same | MITSUI CHEMICALS INC (JP) | 2001-11-14 | — | — | CN | disclosed |
| CN-1050622-C | Polyurethane mixture | ROHM & HAAS (US) | 2000-03-22 | — | — | CN | disclosed |
| CN-1091760-A | Polyurethane mixture | ROHM & HAAS (US) | 1994-09-07 | — | — | CN | disclosed |
| US-3975449-A | NICKEL OR COBALT CATALYST | CHEVRON RESEARCH COMPANY (US) | 1976-08-17 | — | — | US | disclosed |
| US-3956318-A | Hydrogenation of epoxides | CHEVRON RESEARCH COMPANY (US) | 1976-05-11 | — | — | US | disclosed |