Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Dodecane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.73 |
| ▸ | THRB | P10828 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.50 |
| ▸ | CES2 | O00748 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexadecane SCHEMBL3840074 | 1.00 | TSHR (0.73) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| Alcohol SCHEMBL5478963 | 1.00 | TSHR (0.73) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| Decane SCHEMBL8680306 | 1.00 | TSHR (0.73) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| Alcohol SCHEMBL1602280 | 1.00 | TSHR (0.73) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| Undecane SCHEMBL20397396 | 1.00 | TSHR (0.73) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| Heptane SCHEMBL23533257 | 1.00 | TSHR (0.73) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| Decane SCHEMBL424890 | 1.00 | TSHR (0.73) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| Heptane SCHEMBL3790328 | 1.00 | TSHR (0.73) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| Dodecane SCHEMBL5574546 | 1.00 | TSHR (0.73) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| Heptane SCHEMBL11152266 | 1.00 | TSHR (0.73) | TSHRTHRBALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113019404-B | Nickel-based catalyst for synthesizing high-carbon alcohol and preparation method and application thereof | 中国科学院兰州化学物理研究所 | 2022-02-18 | — | — | CN | disclosed |
| CN-113019404-A | Nickel-based catalyst for synthesizing high-carbon alcohol and preparation method and application thereof | 中国科学院兰州化学物理研究所 | 2021-06-25 | — | — | CN | disclosed |
| CN-102460254-B | Waveguide-based detection system with scanning light source | PLC DIAGNOSTICS INC | 2015-05-06 | — | — | CN | disclosed |
| CN-103391767-A | Compositions and methods for treating cardiovascular disease | BIOCOPEA LTD | 2013-11-13 | — | — | CN | disclosed |
| CN-103391768-A | Compostions and methods for treating chronic inflammation and inflammatory diseases | BIOCOPEA LTD | 2013-11-13 | — | — | CN | disclosed |
| CN-102460254-A | Waveguide-based detection system with scanning light source | PLC DIAGNOSTICS INC | 2012-05-16 | — | — | CN | disclosed |
| US-20110200522-A1 | BIMETALLIC CATALYST FOR NOX REDUCTION IN ENGINE EXHAUST | GM Global Technology Operations LLC (US) | 2011-08-18 | — | — | US | disclosed |
| US-7939039-B2 | Bimetallic catalyst for NOx reduction in engine exhaust | GM Global Technology Operations LLC (US) | 2011-05-10 | — | — | US | disclosed |
| US-20090068093-A1 | BIMETALLIC CATALYST FOR NOX REDUCTION IN ENGINE EXHAUST | GM GLOBAL TECHNOLOGY OPERATIONS, INC. (US) | 2009-03-12 | — | — | US | disclosed |
| US-20080085859-A1 | Drug Promoting Ceramide Transport, Base Sequence for Producing the Drug, Method of Measuring Activity of Promoting Ceramide Release and Method of Measuring Activity of Promoting Intermembrane Ceramide Transfer | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2008-04-10 | — | — | US | disclosed |
| US-20060269524-A1 | Composition for nkt cell activation | KIBUN FOOD CHEMIFA CO., LTD. (JP) | 2006-11-30 | — | — | US | disclosed |
| EP-1716857-A1 | COMPOSITION FOR NKT CELL ACTIVATION | Kibun Food Chemifa Co., Ltd. (JP) | 2006-11-02 | — | — | EP | disclosed |
| US-20060198882-A1 | Stable liposomes or micelles comprising a sphinolipid and a peg-lipopolymer | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2006-09-07 | — | — | US | disclosed |
| EP-1652530-A1 | DRUG PROMOTING CERAMIDE TRANSPORT, BASE SEQUENCE FOR PRODUCING THE DRUG, METHOD OF MEASURING ACTIVITY OF PROMOTING CERAMIDE RELEASE AND METHOD OF MEASURING ACTIVITY OF PROMOTING INTERMEMBRANE CERAMIDE TRANSFER | Japan Science and Technology Agency (JP) | 2006-05-03 | — | — | EP | disclosed |
| CN-1243803-C | Water containing printing ink for ink jet recording | MITSUI CHEMICALS INC (JP) | 2006-03-01 | — | — | CN | disclosed |
| CN-1239642-C | Anthraquinone compound and aqueous ink for inkjet recording using the same | MITSUI CHEMICALS INC (JP) | 2006-02-01 | — | — | CN | disclosed |
| US-20050130118-A1 | Methods for identifying inhibitors of chlorophyll synthase | POINTILLIST GLOBAL MACRO SERIES OF POINTILLIST PARTNERS LLC | 2005-06-16 | — | — | US | disclosed |
| CN-1366543-A | Anthraquinone compound and aqueous ink for inkjet recording using the same | MITSUI CHEMICALS INC (JP) | 2002-08-28 | — | — | CN | disclosed |
| CN-1281015-A | Water containing printing ink for ink jet recording | MITSUI CHEMICALS INC (JP) | 2001-01-24 | — | — | CN | disclosed |
| US-5939390-A | LIPIDS FOR TREATMENT OF STRESS INJURIES TO CELLS AND PROTEINS WITH CERAMIDES | NOVO NORDISK A/S (DK) | 1999-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060269524-A1 | Composition for nkt cell activation | GALK1, B4GALT1, MAN2B1 | TSHR 1913/4885THRB 1290/4885ALDH1A1 990/4885 |
| US-20060198882-A1 | Stable liposomes or micelles comprising a sphinolipid and a peg-lipopolymer | SGMS1, SGMS2, PHOSPHO1 | TSHR 3863/4885THRB 4781/4885ALDH1A1 4863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.