Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.41 |
| ▸ | CASR | P41180 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27730686 | 0.89 | POLB (0.50) | POLBSLC6A2SLC6A4SLC6A3AOC3 | |
| SCHEMBL16021853 | 0.85 | POLB (0.43) | POLBSLC6A2SLC6A4SLC6A3AOC3 | |
| SCHEMBL16024187 | 0.81 | CHRM2 (0.47) | SLC6A2SLC6A4SLC6A3L3MBTL1MEN1 | |
| SCHEMBL20385344 | 0.77 | GAA (0.39) | L3MBTL1ALDH1A1 | |
| SCHEMBL18239294 | 0.77 | GAA (0.39) | L3MBTL1ALDH1A1 | |
| SCHEMBL7353471 | 0.74 | EED (0.52) | POLBSLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL28172290 | 0.73 | ACHE (0.57) | HSD11B1PRKDCL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL15271036 | 0.73 | CASR (0.51) | POLBAOC3CASRL3MBTL1ALDH1A1 | |
| SCHEMBL28110010 | 0.72 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3L3MBTL1ALDH1A1 | |
| SCHEMBL3316532 | 0.71 | HTR2C (0.66) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9492460-B2 | Carbazole compounds useful as bromodomain inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-11-15 | — | — | US | disclosed |
| US-20140256700-A1 | CARBAZOLE COMPOUNDS USEFUL AS BROMODOMAIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2014-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256700-A1 | CARBAZOLE COMPOUNDS USEFUL AS BROMODOMAIN INHIBITORS | BRD3, BRD4, BRPF3 | POLB 1233/4885SLC6A2 3969/4885SLC6A4 3868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.