⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16022260 | 0.76 | — | — | |
| SCHEMBL17181784 | 0.75 | NPC1 (0.35) | — | |
| SCHEMBL13034606 | 0.65 | KMT2A (0.39) | — | |
| SCHEMBL13034396 | 0.65 | KMT2A (0.39) | — | |
| SCHEMBL18214735 | 0.62 | POLB (0.34) | — | |
| SCHEMBL19245759 | 0.62 | CNR2 (0.30) | — | |
| SCHEMBL20190046 | 0.62 | APLNR (0.56) | — | |
| SCHEMBL20166323 | 0.62 | APLNR (0.56) | — | |
| SCHEMBL2669133 | 0.61 | RAB9A (0.33) | — | |
| SCHEMBL18618337 | 0.60 | GAA (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140256756-A1 | PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS | ARRAY BIOPHARMA, INC. | 2014-09-11 | — | — | US | disclosed |