Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | BTN3A1 | O00481 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18563093 | 1.00 | PPARG (0.36) | PPARGNCOA2NCOA1RXFP1NCOA3 | |
| SCHEMBL28275107 | 0.86 | BTN3A1 (0.37) | PPARGNCOA2NCOA1RXFP1NCOA3 | |
| SCHEMBL5974187 | 0.86 | CA14 (0.43) | BTN3A1KDM4ETDP1CA12CA1 | |
| SCHEMBL16991699 | 0.86 | BTN3A1 (0.37) | PPARGNCOA2NCOA1RXFP1NCOA3 | |
| SCHEMBL31211706 | 0.84 | ACE (0.41) | PPARGNCOA2NCOA1RXFP1NCOA3 | |
| SCHEMBL21343018 | 0.81 | ALDH1A1 (0.40) | BTN3A1TDP1CA12CA1CA2 | |
| SCHEMBL20181441 | 0.80 | BTN3A1 (0.36) | PPARGNCOA2NCOA1RXFP1NCOA3 | |
| SCHEMBL28197101 | 0.79 | BTN3A1 (0.34) | PPARGNCOA2NCOA1RXFP1NCOA3 | |
| SCHEMBL20249575 | 0.78 | BTN3A1 (0.36) | PPARGNCOA2NCOA1RXFP1NCOA3 | |
| SCHEMBL20249592 | 0.78 | BTN3A1 (0.36) | PPARGNCOA2NCOA1RXFP1NCOA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190276481-A1 | Liver Prodrugs of Mitochondrial Proton Ionophores | NEUROVIVE PHARMACEUTICAL AB (SE) | 2019-09-12 | — | — | US | disclosed |
| WO-2018091633-A1 | LIVER PRODRUGS OF MITOCHONDRIAL PROTON IONOPHORES | NEUROVIVE PHARMACEUTICAL AB (SE) | 2018-05-24 | — | — | WO | disclosed |
| WO-2014135107-A1 | NOVEL NUCLEOSIDE PHOSPHORAMIDATE COMPOUND AND USE THEREOF | 南京圣和药业有限公司 (CN) | 2014-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190276481-A1 | Liver Prodrugs of Mitochondrial Proton Ionophores | GLS2, CYP27A1, SLC25A21 | PPARG 382/4885NCOA2 1020/4885NCOA1 1305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.