SCHEMBL28197101

SCHEMBL28197101

COP(=O)(Cl)NC(C)C(=O)OC(C)C

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BTN3A1 O00481 2/20 0.34
TSHR P16473 1/20 0.32
PPARG P37231 1/20 0.32
NCOA2 Q15596 1/20 0.32
NCOA1 Q15788 1/20 0.32
RXFP1 Q9HBX9 1/20 0.32
NCOA3 Q9Y6Q9 1/20 0.32
NPC1 O15118 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
HPGD P15428 1/20 0.31
CYP2C19 P33261 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CA14 Q9ULX7 1/20 0.31
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL769173 0.82 BTN3A1 (0.36) BTN3A1TSHRPPARGNCOA2NCOA1
SCHEMBL28121930 0.82 BTN3A1 (0.36) BTN3A1TSHRPPARGNCOA2NCOA1
SCHEMBL13471227 0.82 BTN3A1 (0.36) BTN3A1TSHRPPARGNCOA2NCOA1
SCHEMBL16368121 0.81 BTN3A1 (0.39) BTN3A1TSHRPPARGNCOA2NCOA1
SCHEMBL20249592 0.81 BTN3A1 (0.36) BTN3A1TSHRPPARGNCOA2NCOA1
SCHEMBL20249575 0.81 BTN3A1 (0.36) BTN3A1TSHRPPARGNCOA2NCOA1
SCHEMBL15837310 0.81 BTN3A1 (0.39) BTN3A1TSHRPPARGNCOA2NCOA1
SCHEMBL25766390 0.81 TP53 (0.36) BTN3A1TSHRPPARGNCOA2NCOA1
SCHEMBL28855412 0.80 ALDH1A1 (0.41) BTN3A1TSHRALDH1A1FBP1
SCHEMBL16026166 0.79 PPARG (0.36) BTN3A1TSHRPPARGNCOA2NCOA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107709288-A Phosphamide derivative and preparation method and application thereof 四川海思科制药有限公司 2018-02-16 CN disclosed