Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Tetrylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | THPO | P40225 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | G6PD | P11413 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrylammonium SCHEMBL9476357 | 0.98 | LMNA (0.51) | LMNACYP2D6CYP3A4MAPK1THPO | |
| Tetrylammonium SCHEMBL3637947 | 0.94 | LMNA (0.52) | LMNACYP2D6CYP3A4MAPK1THPO | |
| SCHEMBL23754813 | 0.89 | LMNA (0.58) | LMNACYP2D6CYP3A4MAPK1THPO | |
| SCHEMBL8505186 | 0.86 | LMNA (0.55) | LMNACYP2D6CYP3A4MAPK1THPO | |
| SCHEMBL2942432 | 0.86 | LMNA (0.62) | LMNACYP2D6CYP3A4MAPK1THPO | |
| SCHEMBL4660154 | 0.84 | KCNH2 (0.47) | LMNACYP2D6CYP3A4MAPK1THPO | |
| Tetrapropylammonium SCHEMBL330672 | 0.84 | CYP2D6 (0.53) | LMNACYP2D6CYP3A4MAPK1THPO | |
| Tetrylammonium SCHEMBL1815475 | 0.83 | PSIP1 (0.50) | LMNACYP2D6CYP3A4MAPK1THPO | |
| SCHEMBL330892 | 0.83 | LMNA (0.53) | LMNACYP2D6CYP3A4MAPK1THPO | |
| SCHEMBL330725 | 0.83 | KCNH2 (0.70) | LMNACYP2D6CYP3A4MAPK1THPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 944 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025233841-A1 | ELECTROCHEMICAL OXIDATION OF 1,2-CYCLOHEXANEDIOL | INV NYLON CHEMICALS AMERICAS, LLC (US) | 2025-11-13 | — | — | WO | claimed |
| US-20250296952-A1 | METHOD FOR PREPARING ABIRATERONE ACETATE AND INTERMEDIATE THEREOF | AURISCO PHARMACEUTICAL CO., LTD. (CN) | 2025-09-25 | — | — | US | claimed |
| CN-120060868-A | Preparation method of 6-azaspiro [2.5] octane-6-carboxylic acid-1, 1-dimethylethyl ester | 南京药石科技股份有限公司 | 2025-05-30 | — | — | CN | claimed |
| CN-119876972-A | Electrochemical synthesis method of 4' -N-methyl benzyl-3-indole derivative | 深圳职业技术大学 | 2025-04-25 | — | — | CN | claimed |
| CN-117185976-B | Synthesis method of compound L635 | 深圳市灵兰生物医药科技有限公司 | 2024-12-31 | — | — | CN | claimed |
| EP-4464696-A1 | CHEMICALLY DEGRADABLE EPOXY COMPOUND, METHOD FOR PREPARING SAME, EPOXY COMPOSITE MATERIAL COMPRISING SAME, AND DECOMPOSITION METHOD THEREOF | Konkuk University Industrial Cooperation Corp. (KR) | 2024-11-20 | — | — | EP | claimed |
| CN-117304123-B | Preparation method of sun-screening agent Tianlai S | 安徽圣诺贝化学科技有限公司 | 2024-10-01 | — | — | CN | claimed |
| CN-117385378-B | Electrooxidation preparation method and application of electron-deficient aromatic acetal | 厦门大学 | 2024-09-24 | — | — | CN | claimed |
| CN-118048633-A | Method for electrochemically synthesizing trifluoro methylthio oxindole | 上海电力大学 | 2024-05-17 | — | — | CN | claimed |
| CN-117816238-A | Polyethylene nanofiber supported gold-ionic liquid catalyst for catalyzing hydrochlorination of acetylene as well as preparation and application thereof | 浙江工业大学 | 2024-04-05 | — | — | CN | claimed |
| US-4929316-A | Method of manufacturing organic semi-conductor solid electrolytic capacitor | NIKSUKO CORPORATION (JP) | 1990-05-29 | — | — | US | claimed |
| US-4929389-A | POLYPYRROLES, POLYTHIOPHENES, ANISOTROPIC POLYMERS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF ENERGY (US) | 1990-05-29 | — | — | US | claimed |
| US-4880508-A | Water-soluble conductive polymers | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) | 1989-11-14 | — | — | US | claimed |
| WO-1989007957-A1 | CO2 INDICATOR FOR PLACEMENT OF TRACHEAL TUBES | BRIGHAM AND WOMEN'S HOSPITAL (US) | 1989-09-08 | — | — | WO | claimed |
| US-4457810-A | ANODIC OXIDATION OF DI-P-TOLYL ETHER IN PRESENCE OF METHANOL | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-07-03 | — | — | US | claimed |
| EP-0054698-B1 | 4,4'-DIPHENYL ETHER-DIALDEHYDE-BIS-DIMETHYL ACETAL, AND A METHOD FOR ITS PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-06-20 | — | — | EP | claimed |
| US-4399007-A | APPLYING POTENTIAL, CATALYST SELECTIVITY | LEVER BROTHERS COMPANY (US) | 1983-08-16 | — | — | US | claimed |
| EP-0017907-B1 | PROCESS FOR PRODUCING CYCLOHEXENE DERIVATIVES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1983-02-09 | — | — | EP | claimed |
| EP-0054698-A1 | 4,4'-Diphenyl ether-dialdehyde-bis-dimethyl acetal, and a method for its preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-06-30 | — | — | EP | claimed |
| EP-0017907-A1 | Process for producing cyclohexene derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1980-10-29 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250296952-A1 | METHOD FOR PREPARING ABIRATERONE ACETATE AND INTERMEDIATE THEREOF | CYP17A1, CYP21A2, CYP19A1 | LMNA 2133/4885CYP2D6 91/4885CYP3A4 48/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.