Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 7/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | GMNN | O75496 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.48 |
| ▸ | PPARG | P37231 | 6/20 | 0.48 |
| ▸ | PPARD | Q03181 | 6/20 | 0.48 |
| ▸ | PPARA | Q07869 | 6/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| E388 SCHEMBL30341080 | 0.96 | PLA2G4B (0.65) | PLA2G4BHSD17B10GPR84PPARGPPARD | |
| SCHEMBL1603403 | 0.93 | PLA2G4B (0.57) | PLA2G4BHSD17B10GMNNTP53POLB | |
| SCHEMBL1603479 | 0.90 | GPR84 (0.55) | PLA2G4BHSD17B10GMNNTP53POLB | |
| SCHEMBL1603698 | 0.90 | GPR84 (0.55) | PLA2G4BHSD17B10GMNNTP53POLB | |
| SCHEMBL1527381 | 0.89 | HSD17B10 (0.67) | PLA2G4BHSD17B10GMNNTP53POLB | |
| SCHEMBL8865660 | 0.89 | HSD17B10 (0.67) | PLA2G4BHSD17B10GMNNTP53POLB | |
| SCHEMBL3135887 | 0.89 | HSD17B10 (0.67) | PLA2G4BHSD17B10GMNNTP53POLB | |
| SCHEMBL9015776 | 0.89 | HSD17B10 (0.67) | PLA2G4BHSD17B10GMNNTP53POLB | |
| SCHEMBL1603644 | 0.89 | HSD17B10 (0.67) | PLA2G4BHSD17B10GMNNTP53POLB | |
| SCHEMBL9185714 | 0.89 | HSD17B10 (0.67) | PLA2G4BHSD17B10GMNNTP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9663444-B2 | Heteroatom containing substituted fatty acids | COMPLEXA, INC. (US) | 2017-05-30 | — | — | US | disclosed |
| US-20170113999-A9 | HETEROATOM CONTAINING SUBSTITUTED FATTY ACIDS | COMPLEXA, INC. (US) | 2017-04-27 | — | — | US | disclosed |
| US-20140256814-A1 | HETEROATOM CONTAINING SUBSTITUTED FATTY ACIDS | COMPLEXA, INC. (US) | 2014-09-11 | — | — | US | disclosed |
| EP-2483233-A2 | HETEROATOM CONTAINING SUBSTITUTED FATTY ACIDS | Miller, Raymond A. (US) | 2012-08-08 | — | — | EP | disclosed |
| WO-2011041639-A2 | HETEROATOM CONTAINING SUBSTITUTED FATTY ACIDS | MILLER RAYMOND A (US) | 2011-04-07 | — | — | WO | disclosed |
| US-20110082206-A1 | HETEROATOM CONTAINING SUBSTITUTED FATTY ACIDS | COMPLEXA, INC. | 2011-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170113999-A9 | HETEROATOM CONTAINING SUBSTITUTED FATTY ACIDS | FFAR2, FFAR1, FFAR4 | PLA2G4B 129/4885HSD17B10 274/4885GMNN 4270/4885 |
| US-20140256814-A1 | HETEROATOM CONTAINING SUBSTITUTED FATTY ACIDS | FFAR2, FFAR1, FFAR4 | PLA2G4B 129/4885HSD17B10 274/4885GMNN 4270/4885 |
| US-20110082206-A1 | HETEROATOM CONTAINING SUBSTITUTED FATTY ACIDS | FFAR2, FFAR1, FFAR4 | PLA2G4B 129/4885HSD17B10 274/4885GMNN 4270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.