SCHEMBL3135887

SCHEMBL3135887

CCCCCCCCCCCCCCSCCC(=O)O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.67
MAPT P10636 2/20 0.67
GMNN O75496 1/20 0.67
TP53 P04637 1/20 0.67
POLB P06746 1/20 0.67
THRB P10828 1/20 0.67
CYP2C9 P11712 1/20 0.67
BLM P54132 1/20 0.67
PLA2G4B P0C869 1/20 0.63
TDP1 Q9NUW8 3/20 0.61
KMT2A Q03164 3/20 0.61
LMNA P02545 1/20 0.61
GPR84 Q9NQS5 7/20 0.60
PPARG P37231 7/20 0.60
PPARD Q03181 7/20 0.60
PPARA Q07869 7/20 0.60
HDAC11 Q96DB2 5/20 0.60
TSHR P16473 5/20 0.60
PTPN1 P18031 3/20 0.60
ALDH1A1 P00352 2/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL624892 1.00 HSD17B10 (0.67) HSD17B10MAPTGMNNTP53POLB
SCHEMBL1603644 1.00 HSD17B10 (0.67) HSD17B10MAPTGMNNTP53POLB
SCHEMBL28388081 1.00 HSD17B10 (0.67) HSD17B10MAPTGMNNTP53POLB
SCHEMBL28905473 1.00 HSD17B10 (0.67) HSD17B10MAPTGMNNTP53POLB
SCHEMBL9262447 1.00 HSD17B10 (0.67) HSD17B10MAPTGMNNTP53POLB
SCHEMBL9185714 1.00 HSD17B10 (0.67) HSD17B10MAPTGMNNTP53POLB
SCHEMBL8865660 1.00 HSD17B10 (0.67) HSD17B10MAPTGMNNTP53POLB
SCHEMBL9015776 1.00 HSD17B10 (0.67) HSD17B10MAPTGMNNTP53POLB
SCHEMBL1527381 1.00 HSD17B10 (0.67) HSD17B10MAPTGMNNTP53POLB
SCHEMBL11465686 1.00 HSD17B10 (0.67) HSD17B10MAPTGMNNTP53POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107261148-A Methylphenidate prodrug, its preparation and application 凯姆制药公司 2017-10-20 CN claimed
EP-2736510-A2 METHYLPHENIDATE-PRODRUGS, PROCESSES OF MAKING AND USING THE SAME Kempharm, Inc. (US) 2014-06-04 EP claimed
CN-103826633-A Methylphenidate prodrugs, methods of making and using the same KEMPHARM INC 2014-05-28 CN claimed
WO-2013016668-A2 METHYLPHENIDATE-PRODRUGS, PROCESSES OF MAKING AND USING THE SAME KEMPHARM INC. (US) 2013-01-31 WO claimed
CN-122055347-A Oligomeric binaphthyl compounds and thermoplastic resins 三菱瓦斯化学株式会社 2026-05-15 CN disclosed
US-12590065-B2 Levorphanol prodrugs and processes for making and using them ZEVRA THERAPEUTICS, INC. (US) 2026-03-31 US disclosed
US-20260070867-A1 BINAPHTHYL COMPOUNDS AND THERMOPLASTIC RESINS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2026-03-12 US disclosed
CN-114752053-B Polycarbonate resin, method for producing same, and optical lens 三菱瓦斯化学株式会社 2025-05-30 CN disclosed
CN-115960345-B Polycarbonate resin, method for producing same, and optical lens 三菱瓦斯化学株式会社 2025-05-06 CN disclosed
US-20250032479-A1 LEVORPHANOL PRODRUGS AND PROCESSES FOR MAKING AND USING THEM ZEVRA THERAPEUTICS INC (US) 2025-01-30 US disclosed
CN-114716658-B Polycarbonate resin, method for producing same, and optical lens 三菱瓦斯化学株式会社 2024-12-31 CN disclosed
CN-119137185-A Oligomeric binaphthyl compounds and thermoplastic resins 三菱瓦斯化学株式会社 2024-12-13 CN disclosed
EP-0910633-A2 POLYKETIDES AND THEIR SYNTHESIS Biotica Technology Limited (GB) 1999-04-28 EP disclosed
WO-1998001546-A2 POLYKETIDES AND THEIR SYNTHESIS BIOTICA TECHNOLOGY LIMITED (GB) 1998-01-15 WO disclosed
EP-0559898-B1 ANILIDE DERIVATIVE TAISHO PHARMACEUTICAL CO LTD (JP) 1996-05-08 EP disclosed
US-5475130-A A thio, sulfonyl, sulfoxidyl or sulfonate acetamide compound as enzyme inhibitor of acyl-coenzyme A cholesterol acyltransferase TAISHO PHARMACEUTICAL CO., LTD. (JP) 1995-12-12 US disclosed
CN-1082534-A Alkan amido ammonium compound TAISHO PHARMACEUTICAL CO LTD (JP) 1994-02-23 CN disclosed
EP-0559898-A1 ANILIDE DERIVATIVE TAISHO PHARMACEUTICAL CO. LTD (JP) 1993-09-15 EP disclosed
US-4298520-A PHOSPHITES OR PHOSPHATES ARGUS CHEMICAL CORP. (US) 1981-11-03 US disclosed
US-4171298-A SUBSTITUTED ORTHO-ALKYLHYDROXYBENZYLPROPANE-1,3-DIOL ESTERS ARGUS CHEMICAL CORPORATION (US) 1979-10-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250032479-A1 LEVORPHANOL PRODRUGS AND PROCESSES FOR MAKING AND USING THEM OPRM1, OPRL1, OPRK1 HSD17B10 1055/4885MAPT 2544/4885GMNN 2449/4885
US-12590065-B2 Levorphanol prodrugs and processes for making and using them SLC16A3, SLC16A8, SLC16A1 HSD17B10 133/4885MAPT 2316/4885GMNN 4409/4885
US-20260070867-A1 BINAPHTHYL COMPOUNDS AND THERMOPLASTIC RESINS CBR1, CBR3, SCO2 HSD17B10 990/4885MAPT 4394/4885GMNN 2811/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.