SCHEMBL2685891

SCHEMBL2685891

CCOCC1(C(=O)CC)c2ccccc2-c2ccccc21

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
APEX1 P27695 1/20 0.37
ALDH1A1 P00352 1/20 0.36
MAPT P10636 1/20 0.36
ITGA4 P13612 1/20 0.36
PDK2 Q15119 7/20 0.35
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2686052 0.89 THRB (0.38) THRBTDP1APEX1ALDH1A1MAPT
SCHEMBL2687643 0.88 PDK2 (0.37) THRBTDP1APEX1ALDH1A1MAPT
SCHEMBL2686958 0.88 APEX1 (0.38) THRBTDP1APEX1ALDH1A1MAPT
SCHEMBL2686286 0.85 MAPT (0.40) THRBTDP1APEX1ALDH1A1MAPT
SCHEMBL1703815 0.85 PDK2 (0.41) TDP1ALDH1A1MAPTPDK2
SCHEMBL2686340 0.85 MTTP (0.36) APEX1PDK2
SCHEMBL2688290 0.85 SLC25A5 (0.38) THRBTDP1APEX1ALDH1A1MAPT
SCHEMBL2465373 0.84 PDK2 (0.41) TDP1ALDH1A1PDK2
SCHEMBL2688778 0.84 SOAT1 (0.40) PDK2
SCHEMBL2688838 0.83 SOAT1 (0.42) PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3118226-A1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF Corporation (US) 2017-01-18 EP claimed
EP-2782938-B1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF CORP (US) 2016-08-31 EP claimed
EP-2782938-A1 HIGH ACTIVITY CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND METHOD OF USING THE SAME BASF Corporation (US) 2014-10-01 EP claimed
CN-104053682-A High activity catalyst component for olefin polymerization and method of using the same BASF SE 2014-09-17 CN claimed
WO-2013077837-A1 HIGH ACTIVITY CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND METHOD OF USING THE SAME BASF CORPORATION (US) 2013-05-30 WO claimed
US-8227370-B2 High activity catalyst component for olefin polymerization and method of using the same BASF CORPORATION (US) 2012-07-24 US claimed
US-20120116031-A1 High Activity Catalyst Component for Olefin Polymerization and Method of Using the Same BASF CORPORATION (US) 2012-05-10 US claimed
CN-107207657-B Process for preparing spherical polymerization catalyst components for olefin polymerization 格雷斯公司 2020-03-03 CN disclosed
EP-3118226-A1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF Corporation (US) 2017-01-18 EP disclosed
EP-2782938-B1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF CORP (US) 2016-08-31 EP disclosed
US-8227370-B2 High activity catalyst component for olefin polymerization and method of using the same BASF CORPORATION (US) 2012-07-24 US disclosed
US-20120116031-A1 High Activity Catalyst Component for Olefin Polymerization and Method of Using the Same BASF CORPORATION (US) 2012-05-10 US disclosed