SCHEMBL160355

SCHEMBL160355

C=C[Si](C)(C=C)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
TSHR P16473 2/20 0.38
ALDH1A1 P00352 2/20 0.38
BRD4 O60885 1/20 0.35
BRD2 P25440 1/20 0.35
MAPT P10636 1/20 0.35
PTGS1 P23219 1/20 0.34
PTGS2 P35354 1/20 0.34
HDAC8 Q9BY41 1/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
NR1H2 P55055 3/20 0.32
NR1H3 Q13133 3/20 0.32
MAOB P27338 1/20 0.32
AKT1 P31749 1/20 0.31
MMP1 P03956 1/20 0.31
MMP9 P14780 1/20 0.31
LMNA P02545 1/20 0.30
ALOX12 P18054 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5771954 0.86 NR1H2 (0.39) NR1H2NR1H3
SCHEMBL5773688 0.82 TP53 (0.33) BRD4NR1H2NR1H3
SCHEMBL453982 0.79 NR1H2 (0.48) ESR1ESR2TSHRALDH1A1BRD4
SCHEMBL2524118 0.79 ESR1 (0.39) ESR1ESR2TSHRALDH1A1BRD4
SCHEMBL8040579 0.77 ESR1 (0.43) ESR1ESR2TSHRALDH1A1BRD4
SCHEMBL5774858 0.76 HDAC8 (0.34) TSHRALDH1A1HDAC8
SCHEMBL464990 0.75 ESR1 (0.41) ESR1ESR2TSHRALDH1A1MAPT
SCHEMBL10546488 0.75 ESR1 (0.37) ESR1ESR2TSHRALDH1A1MAPT
SCHEMBL4530855 0.75 NR1H2 (0.46) ESR1ESR2TSHRALDH1A1MAPT
SCHEMBL15302395 0.75 ESR1 (0.37) ESR1ESR2TSHRALDH1A1BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 528 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250011621-A1 COMPOSITE COATING, PREPARATION METHOD, AND DEVICE JIANGSU FAVORED NANOTECHNOLOGY CO., LTD. (CN) 2025-01-09 US claimed
EP-4421137-A1 COMPOSITE COATING, PREPARATION METHOD, AND DEVICE Jiangsu Favored Nanotechnology Co., Ltd. (CN) 2024-08-28 EP claimed
WO-2023066103-A1 COMPOSITE COATING, PREPARATION METHOD, AND DEVICE 江苏菲沃泰纳米科技股份有限公司 2023-04-27 WO claimed
US-10059788-B2 Organoaluminum activators on clays EXXONMOBIL CHEMICAL PATENTS INC. (US) 2018-08-28 US claimed
US-20170313799-A1 Organoaluminum Activators on Clays EXXONMOBIL CHEMICAL PATENTS INC. 2017-11-02 US claimed
WO-2017189120-A1 ORGANOALUMINUM ACTIVATORS ON CLAYS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2017-11-02 WO claimed
EP-2881408-B1 Styrene-based copolymer and thermoplastic resin composition including the same LOTTE ADVANCED MAT CO LTD (KR) 2017-09-20 EP claimed
US-9365671-B2 Styrene-based copolymer and thermoplastic resin composition including the same SAMSUNG SDI CO., LTD. (KR) 2016-06-14 US claimed
CN-104088034-B The non-fusible method of polycarbosilane fiber anaerobic and device National University of Defense Technology of People's Liberation Army of China (CN) 2016-02-17 CN claimed
CN-104693334-A Styrene-based copolymer and thermoplastic resin composition including the same SAMSUNG SDI CO LTD 2015-06-10 CN claimed
EP-1245586-A2 Polymer synthesis and films therefrom Shipley Co. L.L.C. (US) 2002-10-02 EP claimed
US-6420441-B1 DISPERSING REMOVABLE CROSSLINKED POLYMER POROGENS IN A POLYSILOXANE, CURING, AND HEATING TO REMOVE POROGEN; LOW DIELECTRIC CONSTANT; HIGH POROSITY; INSULATION MATERIALS SHIPLEY COMPANY, L.L.C. 2002-07-16 US claimed
US-20020065331-A1 Antireflective porogens SHIPLEY COMPANY, L.L.C. 2002-05-30 US claimed
EP-1197998-A2 Antireflective porogens Shipley Company LLC (US) 2002-04-17 EP claimed
EP-1172823-A1 Porous materials Shipley Company LLC (US) 2002-01-16 EP claimed
US-6271273-B1 Porous materials SHIPLEY COMPANY, L.L.C. 2001-08-07 US claimed
CN-1151690-A Dental impression material with cure-indicating dye MINNESOTA MINING & MFG (US) 1997-06-11 CN claimed
EP-0768860-A2 DENTAL IMPRESSION MATERIAL WITH CURE-INDICATING DYE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-04-23 EP claimed
US-5596025-A POLYSILOXANE CURABLE BY HYDROSILATION REACTION, COLOR CHANGE ON CURING MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-01-21 US claimed
WO-1996000560-A2 DENTAL IMPRESSION MATERIAL WITH CURE-INDICATING DYE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-01-11 WO claimed