Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL453982 | 0.95 | NR1H2 (0.48) | NR1H2NR1H3ESR1ESR2ALDH1A1 | |
| SCHEMBL678612 | 0.82 | NR1H2 (0.59) | NR1H2NR1H3 | |
| SCHEMBL12032181 | 0.81 | NR1H2 (0.43) | NR1H2NR1H3ESR1ESR2 | |
| SCHEMBL29262758 | 0.78 | NR1H2 (0.38) | NR1H2NR1H3MAPT | |
| SCHEMBL5772639 | 0.78 | NR1H2 (0.42) | NR1H2NR1H3 | |
| SCHEMBL296774 | 0.76 | ESR1 (0.37) | NR1H2NR1H3ESR1ESR2ALDH1A1 | |
| SCHEMBL10540578 | 0.76 | NR1H2 (0.50) | NR1H2NR1H3 | |
| SCHEMBL2579803 | 0.75 | NR1H2 (0.53) | NR1H2NR1H3 | |
| SCHEMBL2524118 | 0.75 | ESR1 (0.39) | NR1H2NR1H3ESR1ESR2ALDH1A1 | |
| SCHEMBL160355 | 0.75 | ESR1 (0.39) | NR1H2NR1H3ESR1ESR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8197903-B2 | Surface modified organic inorganic hybrid glass, protecting group induced alcohol or its derivative and producing method thereof | INDUSTRY-ACADEMIC COOPERATION FOUNDATION YONSEI UNIVERSITY (KR) | 2012-06-12 | — | — | US | disclosed |
| US-20090274910-A1 | Surface Modified Organic Inorganic Hybrid Glass, Protecting Group Induced Alcohol or Its Derivative and Producing Method Thereof | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2009-11-05 | — | — | US | disclosed |
| WO-2007120014-A1 | SURFACE MODIFIED ORGANIC·INORGANIC HYBRID GLASS, PROTECTING GROUP INDUCED ALCOHOL OR ITS DERIVATIVE AND PRODUCING METHOD THEREOF | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2007-10-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090274910-A1 | Surface Modified Organic Inorganic Hybrid Glass, Protecting Group Induced Alcohol or Its Derivative and Producing Method Thereof | VIM, ICAM1, ILK | NR1H2 4204/4885NR1H3 3750/4885ESR1 3052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.