Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.31 |
| ▸ | TGM2 | P21980 | 1/20 | 0.30 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2235751 | 0.87 | NR1H2 (0.41) | ESR1ESR2NR1H2NR1H3HDAC8 | |
| SCHEMBL160355 | 0.75 | ESR1 (0.39) | ESR1ESR2NR1H2NR1H3MAPT | |
| SCHEMBL453982 | 0.75 | NR1H2 (0.48) | ESR1ESR2NR1H2NR1H3MAPT | |
| SCHEMBL2524118 | 0.75 | ESR1 (0.39) | ESR1ESR2NR1H2NR1H3MAPT | |
| SCHEMBL465010 | 0.75 | TSHR (0.38) | ESR1ESR2NR1H2NR1H3MAPT | |
| SCHEMBL3853122 | 0.75 | TSHR (0.38) | ESR1ESR2NR1H2NR1H3MAPT | |
| SCHEMBL4352107 | 0.75 | TSHR (0.38) | ESR1ESR2NR1H2NR1H3MAPT | |
| SCHEMBL8040579 | 0.73 | ESR1 (0.43) | ESR1ESR2NR1H2NR1H3MAPT | |
| SCHEMBL5701450 | 0.73 | ESR1 (0.35) | ESR1ESR2NR1H2NR1H3MAPT | |
| SCHEMBL19130970 | 0.73 | NR1H2 (0.36) | ESR1ESR2NR1H2NR1H3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 262 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118064115-A | Drilling fluid coating agent and preparation method thereof | 山东诺尔生物科技有限公司 | 2024-05-24 | — | — | CN | claimed |
| CN-115838379-A | Preparation method of methyl phenyl vinyl silanol | 嘉兴联合化学有限公司 | 2023-03-24 | — | — | CN | claimed |
| US-8268489-B2 | Non-aqueous electrolyte solution for lithium secondary battery and lithium secondary battery comprising the same | LG CHEM, LTD. (KR) | 2012-09-18 | — | — | US | claimed |
| US-20110206999-A1 | NON-AQUEOUS ELECTROLYTE SOLUTION FOR LITHIUM SECONDARY BATTERY AND LITHIUM SECONDARY BATTERY COMPRISING THE SAME | LG CHEM, LTD. (KR) | 2011-08-25 | — | — | US | claimed |
| US-7781560-B2 | Curable mixture of an alkoxyalkyl endcapped polysiloxane prepared by reacting a vinyl-terminated polysiloxane with a mono- or disiloxyalkyldisiloxane, an alkylhydrogenpolysiloxane, and organosilicon compound, and a hydrosilation catalyst; has good adhesion to unclean aluminum die castings | DOW CORNING TORAY COMPANY, LTD. (JP) | 2010-08-24 | — | — | US | claimed |
| US-7347970-B2 | Biocides based on silanol terminated silanes and siloxanes | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2008-03-25 | — | — | US | claimed |
| US-20060194764-A1 | Biocides based on silanol terminated silanes and siloxanes | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2006-08-31 | — | — | US | claimed |
| WO-2006028491-A1 | BIOCIDES BASED ON SILANOL TERMINATED SILANES AND SILOXANES | UNIVERSITY OF FLORIDA (US) | 2006-03-16 | — | — | WO | claimed |
| US-6991887-B1 | Photopatternable sorbent and functionalized films | BATTELLE MEMORIAL INSTITUTE (US) | 2006-01-31 | — | — | US | claimed |
| EP-1337897-A4 | PHOTOPATTERNABLE SORBENT AND FUNCTIONALIZED FILMS | BATTELLE MEMORIAL INSTITUTE (US) | 2004-08-04 | — | — | EP | claimed |
| WO-2002036652-A9 | PHOTOPATTERNABLE SORBENT AND FUNCTIONALIZED FILMS | BATTELLE MEMORIAL INSTITUTE (US) | 2004-04-29 | — | — | WO | claimed |
| EP-1337897-A2 | PHOTOPATTERNABLE SORBENT AND FUNCTIONALIZED FILMS | BATTELLE MEMORIAL INSTITUTE (US) | 2003-08-27 | — | — | EP | claimed |
| WO-2002036652-A2 | PHOTOPATTERNABLE SORBENT AND FUNCTIONALIZED FILMS | BATTELLE MEMORIAL INSTITUTE (US) | 2002-05-10 | — | — | WO | claimed |
| EP-0091737-B1 | EXTRUDABLE SILICONE ELASTOMER COMPOSITIONS | DOW CORNING CORPORATION (US) | 1987-08-19 | — | — | EP | claimed |
| US-4427801-A | VINYL ENDCAPPED POLYSILOXANE, ORGANOHYDROGEN POLYSILOXANE, SILICA FILLER | DOW CORNING CORPORATION (US) | 1984-01-24 | — | — | US | claimed |
| EP-0091737-A2 | Extrudable silicone elastomer compositions | DOW CORNING CORPORATION (US) | 1983-10-19 | — | — | EP | claimed |
| CN-115838379-B | Preparation method of methyl phenyl vinyl silanol | 嘉兴联合化学有限公司 | 2026-03-17 | — | — | CN | disclosed |
| CN-115838379-B | Preparation method of methyl phenyl vinyl silanol | 嘉兴联合化学有限公司 | 2026-03-17 | — | — | CN | disclosed |
| US-4268655-A | MERCAPTOORGANO-POLYSILOXANE | DOW CORNING CORPORATION (US) | 1981-05-19 | — | — | US | disclosed |
| US-4087399-A | ORGANO-POLYSILOXANE, SILICA FILLER, PLATINUM, CARBON BLACK, TITANIUM DIOXIDE, AND TRIAZOLE COMPOUND | TORAY SILICONE COMPANY, LTD. (JA) | 1978-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194764-A1 | Biocides based on silanol terminated silanes and siloxanes | MSR1, S1PR3, TAS2R3 | ESR1 713/4885ESR2 610/4885NR1H2 439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.