SCHEMBL5771954

SCHEMBL5771954

C=C[Si](C)(C=C)c1ccc([Si](C)(C=C)C=C)cc1

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 2/20 0.39
NR1H3 Q13133 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29214160 0.87 NFE2L2 (0.38) NR1H2NR1H3
SCHEMBL160355 0.86 ESR1 (0.39) NR1H2NR1H3
SCHEMBL29214136 0.83 NR1H2 (0.47) NR1H2NR1H3
SCHEMBL7635468 0.83 BRD4 (0.46)
SCHEMBL22580535 0.83 NR1H2 (0.43) NR1H2NR1H3
SCHEMBL15863498 0.82
SCHEMBL7635460 0.82 NR1H2 (0.31) NR1H2NR1H3
SCHEMBL5773688 0.78 TP53 (0.33) NR1H2NR1H3
SCHEMBL678612 0.75 NR1H2 (0.59) NR1H2NR1H3
SCHEMBL29249856 0.73 ALOX5 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060134336-A1 Novel polycarbosilane and method of producing the same, film-forming composition, and film and method of forming the same JSR CORPORATION (JP) 2006-06-22 US disclosed
EP-1661934-A1 Polycarbosilane and method of producing the same, film-forming composition, and film and method of forming the same JSR Corporation (JP) 2006-05-31 EP disclosed