Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.75 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.75 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.75 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.75 |
| ▸ | ACE | P12821 | 1/20 | 0.71 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | KDM5C | P41229 | 3/20 | 0.58 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.58 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.58 |
| ▸ | KDM6B | O15054 | 2/20 | 0.58 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.53 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.53 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25203 | 1.00 | LMNA (0.75) | LMNAEGLN1ALKBH5SUCNR1ACE | |
| SCHEMBL22464687 | 1.00 | LMNA (0.75) | LMNAEGLN1ALKBH5SUCNR1ACE | |
| SCHEMBL30203931 | 1.00 | LMNA (0.75) | LMNAEGLN1ALKBH5SUCNR1ACE | |
| SCHEMBL562396 | 1.00 | LMNA (0.75) | LMNAEGLN1ALKBH5SUCNR1ACE | |
| Acetic Acid SCHEMBL9689708 | 0.89 | EGLN1 (0.65) | LMNAEGLN1ALKBH5SUCNR1ACE | |
| SCHEMBL23002867 | 0.87 | SLC22A6 (0.69) | LMNAEGLN1ALKBH5SUCNR1ACE | |
| Succinic Acid SCHEMBL24696 | 0.87 | LMNA (1.00) | LMNAEGLN1ALKBH5SUCNR1ACE | |
| Succinic Acid SCHEMBL4269135 | 0.87 | LMNA (1.00) | LMNAEGLN1ALKBH5SUCNR1ACE | |
| Succinic Acid SCHEMBL21867134 | 0.87 | LMNA (1.00) | LMNAEGLN1ALKBH5SUCNR1ACE | |
| Succinic Acid SCHEMBL3799615 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110082264-A1 | TRANSKETALIZED COMPOSITIONS, SYNTHESIS, AND APPLICATIONS | SEGETIS, INC. (US) | 2011-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110082264-A1 | TRANSKETALIZED COMPOSITIONS, SYNTHESIS, AND APPLICATIONS | TKT, KHK, KYAT3 | LMNA 1269/4885EGLN1 2059/4885ALKBH5 17/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.