Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 1.00 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 1.00 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 1.00 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 1.00 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.67 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.64 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.57 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | KDM5C | P41229 | 2/20 | 0.56 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL8992010 | 1.00 | LMNA (1.00) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL3799615 | 1.00 | — | — | |
| Succinic Acid SCHEMBL1331252 | 1.00 | — | — | |
| Succinic Acid SCHEMBL829 | 1.00 | — | — | |
| Succinic Acid SCHEMBL4269135 | 1.00 | LMNA (1.00) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL29808469 | 1.00 | — | — | |
| Succinic Acid SCHEMBL4269130 | 1.00 | LMNA (1.00) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL1331200 | 1.00 | — | — | |
| Succinic Acid SCHEMBL21867134 | 1.00 | LMNA (1.00) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL28176099 | 1.00 | LMNA (1.00) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 270 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025118084-A1 | EARLY BREAST CANCER DETECTION USING BLOOD-BASED METABOLOMIC PROFILING | BIOMARK CANCER SYSTEMS INC. (CA) | 2025-06-12 | — | — | WO | claimed |
| US-11753635-B2 | Methods and systems and related compositions for mixtures separation with a solid matrix | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2023-09-12 | — | — | US | claimed |
| CN-114505616-A | Solder paste for microwave welding and preparation method and welding method thereof | 深圳市汉尔信电子科技有限公司 | 2022-05-17 | — | — | CN | claimed |
| US-20220049242-A1 | METHODS AND SYSTEMS AND RELATED COMPOSITIONS FOR MIXTURES SEPARATION WITH A SOLID MATRIX | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2022-02-17 | — | — | US | claimed |
| CN-213176777-U | Wear-resistant automobile sealing element | 温州万泰橡塑股份有限公司 | 2021-05-11 | — | — | CN | claimed |
| CN-110777386-B | Multifunctional copper cleaning agent and preparation method thereof | 江南大学 | 2020-09-04 | — | — | CN | claimed |
| CN-110777386-A | Multifunctional copper cleaning agent and preparation method thereof | 江南大学 | 2020-02-11 | — | — | CN | claimed |
| CN-109970706-A | A kind of preparation and refining methd of amber love song Ge Lieting A crystal form | 徐州万邦金桥制药有限公司 | 2019-07-05 | — | — | CN | claimed |
| CN-108530743-A | A kind of plastic formula | 徐州通用高新磁电有限公司 | 2018-09-14 | — | — | CN | claimed |
| CN-103405753-B | Stable insulin secretion accelerating peptide liquid drugs injection pharmaceutical composition | Shanghai Renhui biological pharmaceutical Co., Ltd. (CN) | 2016-05-11 | — | — | CN | claimed |
| CN-101750920-B | Toner | KAO CORP | 2013-06-19 | — | — | CN | claimed |
| CN-103131687-A | Polyethylene glycol covalent modification lysostaphin and prepared method and application thereof | HANGZHOU LION BIOTECHNOLOGY CO LTD | 2013-06-05 | — | — | CN | claimed |
| US-20110136989-A1 | POLYETHERAMIDE COMPOSITIONS | AKZO NOBEL N.V. (NL) | 2011-06-09 | — | — | US | claimed |
| WO-2011058232-A1 | NUTRIGENETIC BIOMARKERS FOR OBESITY AND TYPE 2 DIABETES | MAS-METABOLIC ANALYTICAL SERVICES OY (FI) | 2011-05-19 | — | — | WO | claimed |
| EP-2284540-A1 | Method of diagnosing organ failure | BIOCRATES Life Sciences AG (AT) | 2011-02-16 | — | — | EP | claimed |
| WO-2011012553-A1 | METHOD FOR PREDICTING THE LIKELIHOOD OF AN ONSET OF AN INFLAMMATION ASSOCIATED ORGAN FAILURE | BIOCRATES LIFE SCIENCES AG (AT) | 2011-02-03 | — | — | WO | claimed |
| WO-2011000753-A1 | METHOD FOR NORMALIZATION IN METABOLOMICS ANALYSIS METHODS WITH ENDOGENOUS REFERENCE METABOLITES | BIOCRATES LIFE SCIENCES AG (AT) | 2011-01-06 | — | — | WO | claimed |
| EP-2270699-A1 | Method for normalization in metabolomics analysis methods with endogenous reference metabolites | BIOCRATES Life Sciences AG (AT) | 2011-01-05 | — | — | EP | claimed |
| EP-1068219-B1 | ACYLATED BETULIN AND DIHYDROBETULIN DERIVATIVES, PREPARATION THEREOF AND USE THEREOF | UNIV NORTH CAROLINA (US) | 2006-12-20 | — | — | EP | claimed |
| WO-2004089357-A2 | ANTI-FUNGAL FORMULATION OF TRITERPENE AND ESSENTIAL OIL | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2004-10-21 | — | — | WO | claimed |