Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 4/20 | 0.60 |
| ▸ | TK1 | P04183 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10474572 | 0.81 | TYMP (0.42) | TYMPTK1MAPK1HPGD | |
| SCHEMBL8898025 | 0.81 | TYMP (0.58) | TYMPTK1MAPK1HPGD | |
| Triphosphate SCHEMBL10475447 | 0.80 | TYMP (0.43) | TYMPTK1 | |
| SCHEMBL6998418 | 0.79 | MAPK1 (0.43) | TYMPTK1MAPK1HPGD | |
| SCHEMBL16038187 | 0.77 | PKM (0.43) | TYMP | |
| SCHEMBL15473807 | 0.75 | TYMP (0.41) | TYMPTK1 | |
| SCHEMBL16020642 | 0.75 | TYMP (1.00) | TYMPTK1MAPK1HPGD | |
| SCHEMBL15948684 | 0.75 | TYMP (0.42) | TYMPTK1MAPK1HPGD | |
| SCHEMBL16038194 | 0.75 | TYMP (1.00) | TYMPTK1MAPK1HPGD | |
| SCHEMBL19662195 | 0.72 | ALDH1A1 (0.42) | TYMPTK1MAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10195222-B2 | Acyclic nucleoside phosphonate diesters | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-02-05 | — | — | US | disclosed |
| US-10076532-B2 | Acyclic nucleoside phosphonate diesters | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-09-18 | — | — | US | disclosed |
| US-20180064737-A1 | ACYCLIC NUCLEOSIDE PHOSPHONATE DIESTERS | UNIV CALIFORNIA (US) | 2018-03-08 | — | — | US | disclosed |
| US-20170304330-A1 | ACYCLIC NUCLEOSIDE PHOSPHONATE DIESTERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-10-26 | — | — | US | disclosed |
| US-20170189430-A1 | ACYCLIC NUCLEOSIDE PHOSPHONATE DIESTERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-07-06 | — | — | US | disclosed |
| US-9629860-B2 | Acyclic nucleoside phosphonate diesters | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-04-25 | — | — | US | disclosed |
| US-20140274959-A1 | ACYCLIC NUCLEOSIDE PHOSPHONATE DIESTERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, A CALIFORNIA CORPORATION (US) | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180064737-A1 | ACYCLIC NUCLEOSIDE PHOSPHONATE DIESTERS | NTPCR, PNP, TYMP | TYMP 3/4885TK1 20/4885MAPK1 3713/4885 |
| US-20170189430-A1 | ACYCLIC NUCLEOSIDE PHOSPHONATE DIESTERS | NTPCR, PNP, TYMP | TYMP 3/4885TK1 20/4885MAPK1 3713/4885 |
| US-20140274959-A1 | ACYCLIC NUCLEOSIDE PHOSPHONATE DIESTERS | NTPCR, PNP, TYMP | TYMP 3/4885TK1 20/4885MAPK1 3713/4885 |
| US-10195222-B2 | Acyclic nucleoside phosphonate diesters | NTPCR, PNP, TYMP | TYMP 3/4885TK1 20/4885MAPK1 3713/4885 |
| US-10076532-B2 | Acyclic nucleoside phosphonate diesters | NTPCR, PNP, TYMP | TYMP 3/4885TK1 20/4885MAPK1 3713/4885 |
| US-20170304330-A1 | ACYCLIC NUCLEOSIDE PHOSPHONATE DIESTERS | NTPCR, PNP, TYMP | TYMP 3/4885TK1 20/4885MAPK1 3713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.