Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | SI | P14410 | 2/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8004094 | 0.75 | ALDH1A1 (0.45) | TSHRSMN1; SMN2KMT2ALMNAALDH1A1 | |
| SCHEMBL17075389 | 0.74 | TSHR (0.46) | TSHRSMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL7080788 | 0.73 | TSHR (0.56) | TSHRSMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL28754480 | 0.73 | TSHR (0.44) | TSHRSMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL2914094 | 0.71 | TSHR (0.62) | TSHRKMT2AMEN1LMNAKDM4E | |
| SCHEMBL21056214 | 0.71 | TSHR (0.43) | TSHRSMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL258962 | 0.71 | — | — | |
| SCHEMBL902896 | 0.69 | LMNA (0.43) | TSHRKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL1979159 | 0.68 | TSHR (0.65) | TSHRKMT2AMEN1LMNAKDM4E | |
| SCHEMBL11447443 | 0.68 | TSHR (0.39) | TSHRSMN1; SMN2KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9018316-B2 | Fast degradable polyester polymer and preparation method and use thereof | MOLECON (SUZHOU) NOVEL MATERIALS CO., LTD. (CN) | 2015-04-28 | — | — | US | disclosed |
| US-20140275436-A1 | Fast degradable polyester polymer and preparation method and use thereof | MOLECON (SUZHOU) NOVEL MATERIALS CO., LTD. (CN) | 2014-09-18 | — | — | US | disclosed |