SCHEMBL1603893

SCHEMBL1603893

CCO[SiH2]CCCNc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.53
MAPT P10636 1/20 0.53
KCNH3 Q9ULD8 5/20 0.41
L3MBTL1 Q9Y468 1/20 0.39
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2C19 P33261 1/20 0.37
NPSR1 Q6W5P4 1/20 0.36
NPC1 O15118 1/20 0.35
USP2 O75604 1/20 0.35
TP53 P04637 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HRH3 Q9Y5N1 1/20 0.35
PPARG P37231 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1185279 0.82 MAPT (0.57) ALDH1A1MAPTKCNH3L3MBTL1CYP1A2
SCHEMBL16684623 0.79 ALDH1A1 (0.57) ALDH1A1MAPTKCNH3L3MBTL1CYP1A2
SCHEMBL27297982 0.78 MAPT (0.40) ALDH1A1MAPTL3MBTL1CYP1A2CYP3A4
SCHEMBL3917120 0.78 MAPT (0.52) ALDH1A1MAPTKCNH3L3MBTL1CYP1A2
SCHEMBL3909232 0.78 MAPT (0.52) ALDH1A1MAPTKCNH3L3MBTL1CYP1A2
SCHEMBL29162935 0.76 MAPT (0.64) ALDH1A1MAPTKCNH3L3MBTL1CYP1A2
SCHEMBL1021962 0.76 MAPT (0.48) ALDH1A1MAPTKCNH3L3MBTL1CYP1A2
SCHEMBL25812462 0.75 MAPT (0.52) ALDH1A1MAPTKCNH3L3MBTL1CYP1A2
SCHEMBL825520 0.74 ALDH1A1 (0.47) ALDH1A1MAPTKCNH3L3MBTL1CYP1A2
SCHEMBL825518 0.74 MAPT (0.47) ALDH1A1MAPTKCNH3L3MBTL1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110191701-B Composition for enhancing protein strength 株式会社LG生活健康 2023-02-21 CN claimed
US-20130161864-A1 SUBSTRATE STRUCTURE AND METHOD FOR MAKING THE SAME CHI MEI CORPORATION (TW) 2013-06-27 US disclosed
US-20110082237-A1 Liquid crystal alignment agent, liquid crystal alignment film formed therefrom, and liquid crystal display element provided with the liquid crystal alignment film CHI-MEI CORPORATION 2011-04-07 US disclosed
WO-1998044546-A1 METHOD TO IMPROVE ADHESION OF A THIN SUBMICRON FLUOROPOLYMER FILM ON AN ELECTRONIC DEVICE W.L. GORE & ASSOCIATES, INC. (US) 1998-10-08 WO disclosed