Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 13/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 13/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | FAP | Q12884 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16039876 | 1.00 | CYP3A4 (0.45) | CYP3A4CYP2D6FGFR1SLC22A6FAP | |
| SCHEMBL16038118 | 0.86 | CYP3A4 (0.47) | CYP3A4CYP2D6FGFR1SLC22A6FAP | |
| SCHEMBL19064885 | 0.86 | CYP3A4 (0.47) | CYP3A4CYP2D6FGFR1SLC22A6FAP | |
| SCHEMBL16038063 | 0.85 | CYP3A4 (0.46) | CYP3A4CYP2D6FGFR1SLC22A6FAP | |
| SCHEMBL16037421 | 0.85 | CYP3A4 (0.46) | CYP3A4CYP2D6FGFR1SLC22A6FAP | |
| SCHEMBL28115671 | 0.74 | ADORA2A (0.56) | CYP3A4 | |
| SCHEMBL28350467 | 0.70 | FGFR1 (0.64) | CYP3A4FGFR1SLC22A6FAP | |
| SCHEMBL13997084 | 0.69 | ADORA2A (0.43) | — | |
| SCHEMBL8713742 | 0.68 | FGFR1 (0.46) | CYP3A4FGFR1SLC22A6 | |
| SCHEMBL28025689 | 0.68 | ALDH1A1 (0.46) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10195222-B2 | Acyclic nucleoside phosphonate diesters | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-02-05 | — | — | US | disclosed |
| US-10076532-B2 | Acyclic nucleoside phosphonate diesters | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-09-18 | — | — | US | disclosed |
| US-20180064737-A1 | ACYCLIC NUCLEOSIDE PHOSPHONATE DIESTERS | UNIV CALIFORNIA (US) | 2018-03-08 | — | — | US | disclosed |
| US-20170304330-A1 | ACYCLIC NUCLEOSIDE PHOSPHONATE DIESTERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-10-26 | — | — | US | disclosed |
| US-20170189430-A1 | ACYCLIC NUCLEOSIDE PHOSPHONATE DIESTERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-07-06 | — | — | US | disclosed |
| US-9629860-B2 | Acyclic nucleoside phosphonate diesters | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-04-25 | — | — | US | disclosed |
| US-20140274959-A1 | ACYCLIC NUCLEOSIDE PHOSPHONATE DIESTERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, A CALIFORNIA CORPORATION (US) | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180064737-A1 | ACYCLIC NUCLEOSIDE PHOSPHONATE DIESTERS | NTPCR, PNP, TYMP | CYP3A4 3422/4885CYP2D6 3086/4885FGFR1 3394/4885 |
| US-20170189430-A1 | ACYCLIC NUCLEOSIDE PHOSPHONATE DIESTERS | NTPCR, PNP, TYMP | CYP3A4 3422/4885CYP2D6 3086/4885FGFR1 3394/4885 |
| US-20140274959-A1 | ACYCLIC NUCLEOSIDE PHOSPHONATE DIESTERS | NTPCR, PNP, TYMP | CYP3A4 3422/4885CYP2D6 3086/4885FGFR1 3394/4885 |
| US-10195222-B2 | Acyclic nucleoside phosphonate diesters | NTPCR, PNP, TYMP | CYP3A4 3422/4885CYP2D6 3086/4885FGFR1 3394/4885 |
| US-10076532-B2 | Acyclic nucleoside phosphonate diesters | NTPCR, PNP, TYMP | CYP3A4 3422/4885CYP2D6 3086/4885FGFR1 3394/4885 |
| US-20170304330-A1 | ACYCLIC NUCLEOSIDE PHOSPHONATE DIESTERS | NTPCR, PNP, TYMP | CYP3A4 3422/4885CYP2D6 3086/4885FGFR1 3394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.